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(A–D) Four Classes of Heterocyclic A3AR Allosteric Modulators [Amiloride Derivative 1 (A), 3-(2-Pyridinyl)isoquinoline 2 (B), 2,4-Disubstituted Quinoline 3 (C), and 1H-Imidazo[4,5-c]quinolin-4-amines with 2-Alkyl and 2-Cycloalkyl Substitutions (4–12) (D), Including Alternative 4-Substituted Phenylamino Derivatives and the Bulky 2-Bicycloalkyl (exo-Norbornanyl, 12a) and 2-Tricycloalkyl (Adamantan-1-yl, 12b) Derivatives (E)19,20
