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. 2023 May 4;8(4):e10528. doi: 10.1002/btm2.10528

TABLE 2.

Plasma‐induced macrophage polarization.

The polarization direction of macrophages Treated cells Application Plasma source Plasma treatment parameters Ref.
Proinflammatory M1 Human THP‐1 monocytic model cell Glioblastoma multiforme (GBM) treatment μ‐DBD 24 kHz, 0.04 w, 1 L/min (N2), 1.2 kV, 2.6 mA, 1 min and 3 min 43
A “M0/M2‐like” phenotype Resting M0 macrophages from human plasma of 10 healthy donors Melanoma treatment APPJ MiniJet‐R 2.45 GHz, level 4, 2 L/min (Ar), 30 s, 60 s, 120 s 44
Promoted M1 to M2 phenotypic shift in an inflammatory microenvironment The murine macrophage cell line (RAW264.7) Periodontal regeneration kINPen 09 Activated PAM 1.7 MHz, 2–6 kV, 5 L/min (Ar), 10 min This project