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. 2023 Jul 6;36(7):1107–1120. doi: 10.1021/acs.chemrestox.3c00086

Table 2. Overview of the Overlap between the Mitochondrial Toxicity Datasets and the Active Profiles from the Cell Painting Data Used for Modeling (Cell Painting Datasets).

Endpoint Total Active Inactive
Overall 681 193 488
Membrane potential 643 158 485
Respiratory chain 166 78 88
Function of mitochondria 179 91 88
Tox21 test set 60 17 43
Bayer 27 14 13