Table 2. Overview of the Overlap between the Mitochondrial Toxicity Datasets and the Active Profiles from the Cell Painting Data Used for Modeling (Cell Painting Datasets).
Endpoint | Total | Active | Inactive |
---|---|---|---|
Overall | 681 | 193 | 488 |
Membrane potential | 643 | 158 | 485 |
Respiratory chain | 166 | 78 | 88 |
Function of mitochondria | 179 | 91 | 88 |
Tox21 test set | 60 | 17 | 43 |
Bayer | 27 | 14 | 13 |