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. 2023 Jul 6;36(7):1107–1120. doi: 10.1021/acs.chemrestox.3c00086

Table 5. Performance of the Models Developed in this Study and Literature Models on an External Test Set of Membrane Potential Loss.

Model Method MCC F1 score Recall Precision Specificity
Overall NN 0.48 0.54 0.68 0.45 0.88
Membrane potential NN 0.57 0.62 0.66 0.59 0.94
Hemmerich et al.8,a NN 0.53 0.59 0.57 0.61 0.95
Bringezu et al.40,a Ensemble of undersampled gradient boosting models 0.61 - 0.92 - 0.87
a

Results taken from the original papers; not recalculated.