Table 2. Reactivity of 23 Aromatic Aldehydes toward Glycine-pNA (Gly-pNA) Employing a DPRA-like Setup in Terms of 24 h Depletion (D_Gly) as well as Literature Data on 24 h DPRA Lysine Depletion (D_DPRA-Lys; Aqueous Medium, pH 7.5) and 6 h Butyl Amine Depletion (D_BuAmin; Water-Poor Medium), Respectively.

			literature reactivity profilea
compound	no	DGly 24 h [%] (aqueous, pH 7.4)	DDPRA-Lys 24 h [%] (aqueous, pH 7.5)	DBuAmin 6 h [%] (water-poor)
benzaldehyde	A1	8.8 ± 1.6	8.8	95.4
2-methyl benzaldehyde	A2	11.9 ± 0.3
3-methyl benzaldehyde	A3	7.4 ± 0.4
4-methyl benzaldehyde	A4	3.1 ± 0.4	5.1	90.9
4-isopropyl benzaldehyde	B1	3.8 ± 0.5	12.5	81.0
2-hydroxy benzaldehyde	B2	5.5 ± 0.4	27.3	97.2
3-hydroxy benzaldehyde	B3	5.8 ± 1.1	0.9	26.4
4-hydroxy benzaldehyde	B4	1.8 ± 0.6	0	0
2-methoxy benzaldehyde	C1	11.2 ± 0.6
3-methoxy benzaldehyde	C2	10.9 ± 0.4	0	90.4
4-methoxy benzaldehyde	C3	1.9 ± 0.2	0	25.9
3-nitro benzaldehyde	C4	46.8 ± 1.3
4-nitro benzaldehyde	D1	76.1 ± 1.2	0	54.5
4-chlorobenzaldehyde	D2	14.8 ± 0.6	35.8	91.3
vanillin	D3	0.4 ± 0.2	2.2	0
ethyl vanillin	D4	0.5 ± 0.3	3.1	0
3,4-dimethoxy benzaldehyde	E1	1.1 ± 0.8	0	9.4
4-methoxy-3-hydroxy benzaldehyde	E2	1.4 ± 0.2
3-chloro-4-methoxy benzaldehyde	E3	2.9 ± 0.3	4.4	14.9
2-bromo-5-hydroxy benzaldehyde	E4	54.9 ± 2.4	0	90.8
6-methoxy naphthalene carbaldehyde	F1	2.1 ± 0.4	0	15.0
atranol	F2	11.3 ± 3.6	60.1	94.3
chloratranol	F3	16.5 ± 2.5	60.5	95.3

^aLysine and butyl amine depletion taken from literature.¹¹