Table 1. Screening of Lipases for the Enzymatic Acetylation of HMFA (3)a.

| entry | enzyme | 7a (%)b |
|---|---|---|
| 1 | <3 | |
| 2 | Novozyme 435 | >99 |
| 3 | EziG-CALB | >99 |
| 4 | TLL | 83 |
| 5 | PSL | 69 |
| 6 | AK | 31 |
Reaction conditions: 3 (100 mM in 2-MeTHF), 1.3 equiv of 5a, and 1:1 w/w enzyme:3 ratio for 24 h at 30 °C and 250 rpm.
Conversion calculated by GC analyses of the reaction crudes (see the SI for details).