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. 2023 Jul 6;11(28):10284–10292. doi: 10.1021/acssuschemeng.3c00775

Table 1. Screening of Lipases for the Enzymatic Acetylation of HMFA (3)a.

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entry enzyme 7a (%)b
1   <3
2 Novozyme 435 >99
3 EziG-CALB >99
4 TLL 83
5 PSL 69
6 AK 31
a

Reaction conditions: 3 (100 mM in 2-MeTHF), 1.3 equiv of 5a, and 1:1 w/w enzyme:3 ratio for 24 h at 30 °C and 250 rpm.

b

Conversion calculated by GC analyses of the reaction crudes (see the SI for details).