Table 1.
Possible factors may be associated with healthy cases and bipolar disorder patients.
| Characteristics | HG (n = 102) | BD (n = 470) | p |
|---|---|---|---|
| Age(years) | 37.00(30.00–43.00) | 34.00(27.00–47.00) | 0.354 |
| Gender | 0.239 | ||
| male (n, %) | 38(37.3%) | 205(43.6%) | |
| female (n, %) | 64(62.7%) | 265(56.4%) | |
| Body mass index (kg/m2) | 23.88(22.26–26.73) | 24.45(22.09–27.39) | 0.640 |
| WBC (109/L) | 5.60(5.00–6.55) | 6.50(5.30–8.20) | <0.0001 |
| NEU (109/L) | 3.20(2.60–3.80) | 3.80(2.80–5.13) | <0.0001 |
| LYM (109/L) | 1.90(1.60–2.40) | 1.90(1.50–2.40) | 0.605 |
| MON (109/L) | 0.40(0.30–0.50) | 0.50(0.40–0.63) | <0.0001 |
| RBC (1012/L) | 4.61 ± 0.42 | 4.45 ± 0.50 | 0.005 |
| HGB(g/L) | 136.00(127.75–149.25) | 134.00(122.75–146.00) | 0.071 |
| PLT (109/L) | 248.50(210.00–287.50) | 237.00(202.00–274.00) | 0.168 |
| hs-CRP (mg/L) | 1.10(0.65–1.81) | 1.46(0.58–3.84) | 0.010 |
| NLR | 1.58(1.31–2.02) | 1.89(1.38–2.90) | <0.0001 |
| MLR | 0.20(0.16–0.24) | 0.25(0.20–0.36) | <0.0001 |
| PLR | 126.92(102.02–152.54) | 124.19(95.49–158.78) | 0.747 |
| NHR | 2.54(1.91–3.36) | 3.32(2.25–4.62) | <0.0001 |
| LHR | 1.63(1.23–1.94) | 1.56(1.19–2.17) | 0.755 |
| MHR | 0.31(0.23–0.42) | 0.41(0.30–0.57) | <0.0001 |
| PHR | 198.09(166.20–254.38) | 200.36(157.98–242.78) | 0.513 |
| SII | 386.56(294.37–506.79) | 456.32(312.94–713.04) | 0.004 |
| SIRI | 0.61(0.43–0.82) | 0.94(0.58–1.60) | <0.0001 |
HG, Healthy group; BD, bipolar disorder; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte; MON, monocyte; RBC, red blood cell; HGB, hemoglobin; PLT, platelet; hs-CRP, hypersensitive C-reactive protein; NLR, Neutrophil-to-lymphocyte ratio; MLR, Monocyte-to-lymphocyte ratio; PLR, Platelet-to-lymphocyte ratio; NHR, Neutrophil-to-HDL ratio; LHR, lymphocyte-to-HDL ratio; MHR, Monocyte-to-HDL ratio; PHR, Platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index; SIRI, system inflammation response index.