Table 2.
Possible factors may be associated with healthy cases and bipolar disorder manic episodes.
| Characteristics | HG (n = 102) | BD-M (n = 322) | p |
|---|---|---|---|
| Age(years) | 37.00(30.00–43.00) | 34.00(28.00–45.00) | 0.279 |
| Gender | 0.403 | ||
| male (n, %) | 38(37.3%) | 135(41.9%) | |
| female (n, %) | 64(62.7%) | 187(58.1%) | |
| Body mass index (kg/m2) | 23.88(22.26–26.73) | 24.67(22.45–27.68) | 0.324 |
| WBC (109/L) | 5.60(5.00–6.55) | 6.90(5.48–8.40) | <0.0001 |
| NEU (109/L) | 3.20(2.60–3.80) | 3.90(2.98–5.36) | <0.0001 |
| LYM (109/L) | 1.90(1.60–2.40) | 1.90(1.50–2.48) | 0.637 |
| MON (109/L) | 0.40(0.30–0.50) | 0.5(0.40–0.70) | <0.0001 |
| RBC (1012/L) | 4.61 ± 0.42 | 4.44 ± 0.50 | 0.003 |
| HGB(g/L) | 136.00(127.75–149.25) | 134.00(121–146) | 0.048 |
| PLT (109/L) | 248.50(210.00–287.50) | 237.00(203.75–278.25) | 0.235 |
| hs-CRP (mg/L) | 1.10(0.65–1.18) | 1.73(0.71–4.45) | <0.0001 |
| NLR | 1.58(1.31–2.02) | 1.93(1.42–3.09) | <0.0001 |
| MLR | 0.20(0.16–0.24) | 0.27(0.2–0.38) | <0.0001 |
| PLR | 126.92(102.02–152.54) | 124.77(94.48–223.26) | 0.896 |
| NHR | 2.54(1.91–3.36) | 3.57(2.36–4.78) | <0.0001 |
| LHR | 1.63(1.23–1.94) | 1.55(1.18–2.24) | 0.855 |
| MHR | 0.31(0.23–0.42) | 0.45(0.32–0.58) | <0.0001 |
| PHR | 198.09(166.20–254.38) | 202.22(159.13–242.60) | 0.632 |
| SII | 386.56(294.37–506.79) | 473.80(316.83–748.79) | 0.001 |
| SIRI | 0.61(0.43–0.82) | 1.04(0.60–1.89) | <0.0001 |
HG, Healthy group; BD-M, bipolar disorder manic episodes; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte; MON, monocyte; RBC, red blood cell; HGB, hemoglobin; PLT, platelet; hs-CRP, hypersensitive C-reactive protein; NLR, Neutrophil-to-lymphocyte ratio; MLR, Monocyte-to-lymphocyte ratio; PLR, Platelet-to-lymphocyte ratio; NHR, Neutrophil-to-HDL ratio; LHR, lymphocyte-to-HDL ratio; MHR, Monocyte-to-HDL ratio; PHR, Platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index; SIRI, system inflammation response index.