Table 3.
Possible factors may be associated with healthy cases and bipolar disorder depressive episodes.
| Characteristics | HG (n = 102) | BD-D (n = 105) | p |
|---|---|---|---|
| Age(years) | 37.00(30.00–43.00) | 37.00(24.50–53.00) | 0.937 |
| Gender | |||
| male (n, %) | 38(37.3%) | 50(47.6%) | 0.132 |
| female (n, %) | 64(62.7%) | 55(52.4%) | |
| Body mass index (kg/m2) | 23.88(22.26–26.73) | 24.01(21.28–26.76) | 0.372 |
| WBC (109/L) | 5.60(5.00–6.55) | 5.90(4.85–7.25) | 0.346 |
| NEU (109/L) | 3.20(2.60–3.80) | 3.36(2.61–4.30) | 0.145 |
| LYM (109/L) | 1.90(1.60–2.40) | 1.90(1.50–2.20) | 0.266 |
| MON (109/L) | 0.40(0.30–0.50) | 0.40(0.33–0.57) | 0.002 |
| RBC (1012/L) | 4.61 ± 0.42 | 4.46 ± 0.53 | 0.025 |
| HGB(g/L) | 136.90 ± 15.75 | 134.36 ± 15.04 | 0.239 |
| PLT (109/L) | 248.50(210.00–287.50) | 235.00(198.50–274.00) | 0.132 |
| hs-CRP (mg/L) | 1.10(0.65–1.18) | 1.00(0.38–2.17) | 0.524 |
| NLR | 1.58(1.31–2.02) | 1.86(1.30–2.36) | 0.030 |
| MLR | 0.20(0.16–0.24) | 0.24(0.19–0.30) | <0.0001 |
| PLR | 126.92(102.02–152.54) | 125.79(102.42–155.13) | 0.964 |
| NHR | 2.54(1.91–3.36) | 2.84(2.06–4.24) | 0.020 |
| LHR | 1.63(1.23–1.94) | 1.60(1.25–2.09) | 0.602 |
| MHR | 0.31(0.23–0.42) | 0.36(0.27–0.55) | 0.002 |
| PHR | 198.09(166.20–254.38) | 200.75(154.74–250.98) | 0.798 |
| SII | 386.56(294.37–506.79) | 420.43(302.12–622.07) | 0.247 |
| SIRI | 0.61(0.43–0.82) | 0.78(0.50–1.15) | 0.001 |
HG, Healthy group; BD-D, bipolar disorder depressive episodes; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte; MON, monocyte; RBC, red blood cell; HGB, hemoglobin; PLT, platelet; hs-CRP, hypersensitive C-reactive protein; NLR, Neutrophil-to-lymphocyte ratio; MLR, Monocyte-to-lymphocyte ratio; PLR, Platelet-to-lymphocyte ratio; NHR, Neutrophil-to-HDL ratio; LHR, lymphocyte-to-HDL ratio; MHR, Monocyte-to-HDL ratio; PHR, Platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index; SIRI, system inflammation response index.