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. 2023 Jul 5;14:1219151. doi: 10.3389/fpsyt.2023.1219151

Table 4.

Possible factors may be associated with healthy cases and bipolar disorder with mixed features.

Characteristics HG (n = 102) BD with mixed features (n = 43) p
Age(years) 37.00(30.00–43.00) 33.00(29.00–45.00) 0.245
Gender 0.299
male (n, %) 38(37.3%) 20(46.5%)
female (n, %) 64(62.7%) 23(53.5%)
Body mass index (kg/m2) 23.88(22.26–26.73) 24.41(21.88–26.83) 0.883
WBC (109/L) 5.60(5.00–6.55) 6.70(5.50–8.90) 0.002
NEU (109/L) 3.20(2.60–3.80) 3.40(2.81–5.90) 0.030
LYM (109/L) 1.90(1.60–2.40) 2.00(1.70–2.38) 0.375
MON (109/L) 0.40(0.30–0.50) 0.50(0.40–0.60) <0.0001
RBC (1012/L) 4.61 ± 0.42 4.53 ± 0.44 0.366
HGB(g/L) 136.00(127.75–149.25) 137.00(124.00–149.00) 0.797
PLT (109/L) 248.50(210.00–287.50) 244.00(203.00–267.00) 0.497
hs-CRP (mg/L) 1.10(0.65–1.18) 0.90(0.48–2.37) 0.962
NLR 1.58(1.31–2.02) 1.70(1.33–2.93) 0.115
MLR 0.20(0.16–0.24) 0.24(0.20–0.31) 0.001
PLR 126.92(102.02–152.54) 110.24(90.34–150.00) 0.112
NHR 2.54(1.91–3.36) 2.90(1.96–5.06) 0.087
LHR 1.63(1.23–1.94) 1.64(1.20–2.15) 0.825
MHR 0.31(0.23–0.42) 0.38(0.30–0.51) 0.003
PHR 198.09(166.20–254.38) 188.32(147.11–223.53) 0.116
SII 386.56(294.37–506.79) 438.89(312.08–758.43) 0.197
SIRI 0.61(0.43–0.82) 0.73(0.65–1.32) <0.0001

HG, Healthy group; BD with mixed features, bipolar disorder with mixed features; WBC, white blood cell; NEU, neutrophil; LYM, lymphocyte; MON, monocyte; RBC, red blood cell; HGB, hemoglobin; PLT, platelet; hs-CRP, hypersensitive C-reactive protein; NLR, Neutrophil-to-lymphocyte ratio; MLR, Monocyte-to-lymphocyte ratio; PLR, Platelet-to-lymphocyte ratio; NHR, Neutrophil-to-HDL ratio; LHR, lymphocyte-to-HDL ratio; MHR, Monocyte-to-HDL ratio; PHR, Platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index; SIRI, system inflammation response index.