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. 2023 Jul 5;14:1219151. doi: 10.3389/fpsyt.2023.1219151

Table 5.

Predictors for bipolar disorder in different states by multivariate analysis.

B S.E p value Odds ratio 95% CI
Lower limit Upper limit
HG vs BD
MON 5.083 0.971 <0.0001 161.257 24.065 1080.585
hs-CRP 0.174 0.073 0.018 1.190 1.031 1.374
NLR 1.036 0.327 0.002 2.819 1.484 5.354
Constant 2.151 1.168 0.065 8.593
HG vs BD-M
MON 5.375 1.011 <0.0001 215.916 29.737 1567.718
hs-CRP 0.211 0.084 0.012 1.235 1.048 1.457
NLR 1.022 0.335 0.002 2.779 1.440 5.360
Constant 1.520 1.291 0.239 4.571
HG vs BD-D
NLR 0.544 0.200 0.006 1.723 1.165 2.549
MHR 4.208 1.066 <0.0001 67.212 8.322 542.860
Constant 3.244 1.495 0.030 25.632
HG vs BD with mixed features
MON 5.454 1.718 0.001 233.805 8.065 6778.348
Constant −4.308 0.822 <0.0001 0.013

HG, Healthy group; BD, bipolar disorder; BD-M, bipolar disorder manic episodes; BD-D, bipolar disorder depressive episodes; BD with mixed features, bipolar disorder with mixed features; MON, monocyte; hs-CRP, hypersensitive C-reactive protein; NLR, Neutrophil-to-lymphocyte ratio; MHR, Monocyte-to-HDL ratio.