Table 1.
Baseline Demographics at the Start of Omadacycline Treatment
| Characteristic | No. (%) |
|---|---|
| Total No. of subjects | 117 |
| Age, y, mean ± SD | 55.1 ± 18.9 |
| Female sex | 76 (65) |
| Race/ethnicity | |
| White | 96 (82) |
| African American | 4 (3.4) |
| Asian | 12 (10) |
| Non-white Hispanic | 3 (2.6) |
| Other | 2 (2) |
| Insurance coverage (n = 93a) | |
| Private | 49 (53) |
| Medicare | 39 (42) |
| Medicaid | 4 (4) |
| Other | 1 (1) |
| BMI, kg/m2, mean ± SD | 21.7 ± 4.4 |
| FEV1 (% predicted), mean ± SD (n = 71) | 69.74 ± 20.9 |
| Tobacco history (n = 95b) | |
| Current | 0 (0) |
| Former | 28 (29) |
| Never | 67 (71) |
| Primary classification of infection site | |
| Pulmonary | 94 (80) |
| Skin and soft tissue | 12 (10) |
| Multiple sites of infectionc | 6 (5) |
| Peritonitis | 3 (3) |
| Disseminatedd | 1 (1) |
| Bone/joint | 1 (1) |
| Other medical condition | |
| Gastroesophageal reflux disease | 59 (50.4) |
| Depression/anxiety | 30 (25.6) |
| Diabetes mellitus | 15 (12.8) |
| Connective tissue disease | 12 (10.3) |
| Immunodeficiencye | 11 (9.4) |
| Transplant recipientf | 10 (8.5) |
| Chronic kidney disease | 10 (8.5) |
| Active malignancy | 8 (6.8) |
Data are presented as No. (%) unless otherwise indicated. There were 117 subjects included in the overall dataset, but denominators for categories with missing data are acknowledged accordingly.
Abbreviations: BMI, body mass index; FEV1, forced expiratory volume in 1 second; SD, standard deviation.
Total number of participants is reduced as 1 participating site did not have access to patient insurance status.
Tobacco use history was only recorded for patients with diagnosis of nontuberculous pulmonary disease.
Multiple sites of infection include involvement of >1 of the following sites in any combination: pulmonary, bone and joint, and/or skin and soft tissue.
The infection considered to be disseminated involved multiple extrapulmonary lymph nodes.
This was reported as hypogammaglobulinemia in 2 patients and no further data were provided for others.
Transplant type: lung (n = 6), kidney (n = 2), stem cell transplant (n = 2).