Table 2.
Change in serum creatinine before and after the diagnosis of AKI
| Variables | Values |
|---|---|
| Original cohort | |
| Serum creatinine at ICU admission, mean ± SD | 1.63 ± 0.94 |
| Serum creatinine at ICU admission, median (IQR) | 1.00 (0.70, 1.80) |
| Serum creatinine at first AKI diagnosis, mean ± SD | 2.40 ± 1.04 |
| Serum creatinine at first AKI diagnosis, median (IQR) | 1.70 (1.20–2.90) |
| Serum creatinine at 48 h after AKI diagnosis, mean ± SD | 2.12 ± 1.02 |
| Serum creatinine at 48 h after AKI diagnosis, median (IQR) | 1.50 (0.93–2.68) |
| Positive changes of serum creatinine, n (%) | 1193 (22.4) |
| Δserum creatinine, mean ± SD | 0.86 ± 0.73 |
| Negative or static change of serum creatinine, n (%) | 4131 (77.6) |
| Δserum creatinine, mean ± SD | -0.63 ± 0.51 |
| Validation cohort | |
| Serum creatinine at ICU admission, mean ± SD | 1.53 ± 0.52 |
| Serum creatinine at ICU admission, median (IQR) | 1.08 (0.72, 1.90) |
| Serum creatinine at first AKI diagnosis, mean ± SD | 2.74 ± 1.04 |
| Serum creatinine at first AKI diagnosis, median (IQR) | 2.10 (1.38, 3.49) |
| Serum creatinine at 48 h after AKI diagnosis, mean ± SD | 2.12 ± 1.02 |
| Serum creatinine at 48 h after AKI diagnosis, median (IQR) | 1.50 (0.93, 2.68) |
| Positive changes of serum creatinine, n (%) | 333 (14.3) |
| Δserum creatinine, mean ± SD | 0.53 ± 0.42 |
| Negative or static change of serum creatinine, n (%) | 1989 (85.7) |
| Δserum creatinine, mean ± SD | -0.81 ± 0.67 |
ICU, intensive care unit, SD, standard deviation, IQR, interquartile range, AKI, acute kidney injury