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. 2023 Jul 18;23:514. doi: 10.1186/s12888-023-05014-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effects of minocycline, risperidone and haloperidol on LPS induced morphological changes in BV2 cells. The cells were randomly divided into 5 groups. The blank control group (A) was treated with nothing, the LPS group (B) was treated with 1.0 ug/ml LPS for 24 h. The three drug groups were pretreated with 10 μmol/L minocycline (C), 10 μmol/L risperidone (D) and 50 μmol/L haloperidol (E) respectively for 24 h, and then 1.0 ug/ml LPS was added for 24 h. The morphology of BV2 cells was observed under 400X-ray light microscope. Each group chose one of the three separate images as a representative. Scale bar in Fig.A is 15 μm, in Fig.B-E is 25 μm. The bar chart (F) shows statistical results of WB. ^###p < 0.001 was compared with the blank control group; **p < 0.01 and ***p < 0.001 were compared with the LPS group.