Table 3.
Haplotype analysis of IL23R gene SNPs associated with the severity of TB
| Haplotypes | Severe TB N(%) | Mild TB N(%) | ORa(95% CI) | Pa |
|---|---|---|---|---|
| GAG | 202(18.1) | 193(16.7) | 1.100(0.885–1.367) | 0.39 |
| GGA | 45(4.0) | 32(2.8) | 1.473(0.929–2.335) | 0.10 |
| GGG | 189(17.0) | 176(15.2) | 1.134(0.906–1.419) | 0.27 |
| TAG | 86(7.7) | 88(7.6) | 1.013(0.743–1.382) | 0.93 |
| TGA | 510(45.7) | 550(47.5) | 0.923(0.782–1.089) | 0.34 |
| TGG | 75(6.8) | 106(9.2) | 0.715(0.526–0.973) | 0.032 |
Abbreviation: TB tuberculosis; SNPs single nucleotide polymorphisms; OR odds ratio; CI confidence interval; a, adjusted for age and gender