Table 2.

Risk and protective factors for mechanically ventilated patients

Characteristics	Total(N)	Univariate analysis		Multivariate analysis
		Odds Ratio (95% CI)	P-value	Odds Ratio (95% CI)	P-value
Sex	3301
Female	1074	Reference
Male	2227	1.150 (0.945–1.400)	0.163
Age	3301
< 60	1698	Reference		Reference
≥ 60	1603	1.738 (1.446–2.089)	< 0.001	1.600 (1.220–2.100)	0.001
aCCI	3301	1.200 (1.145–1.258)	< 0.001	1.038 (0.948–1.136)	0.423
SOFA	3301	1.151 (1.117–1.185)	< 0.001	1.076 (1.029–1.125)	0.001
MAP, mmHg	3301	0.983 (0.978–0.987)	< 0.001	0.995 (0.989–1.001)	0.095
FIO2	3301	0.997 (0.990–1.005)	0.517
PCO2, mmHg	3301	0.957 (0.947–0.968)	< 0.001	0.968 (0.955–0.982)	< 0.001
PO2, mmHg	3301	0.996 (0.989–1.002)	0.164
WBC, 1012/L	3301	1.005 (0.999–1.011)	0.119
PLT, 109/L	3301	0.998 (0.997–0.999)	< 0.001	1.001 (0.999–1.002)	0.333
Lac, mmol/L	3301	1.203 (1.140–1.270)	< 0.001	1.250 (1.138–1.374)	< 0.001
APTT, S	3301	1.024 (1.013–1.035)	< 0.001	1.002 (0.990–1.014)	0.762
Urine, mL	3283	1.000 (1.000–1.000)	0.433
ALT, U/L	3301	1.001 (1.000–1.001)	0.016	1.000 (0.999–1.001)	0.691
AST, U/L	3301	1.000 (1.000–1.001)	0.021	0.999 (0.999–1.000)	0.003
BUN, mmol/L	3301	1.021 (1.008–1.035)	0.002	0.959 (0.933–0.985)	0.002
Cr, µmol/L	3301	1.001 (1.000–1.001)	0.029	1.001 (1.000–1.002)	0.073
BMI, kg/m2	3301	0.902 (0.876–0.928)	< 0.001	0.899 (0.873–0.925)	< 0.001
Congestive Heart Failure	2542	1.162 (0.932–1.450)	0.183
Renal failure	968	1.468 (1.213–1.776)	< 0.001	1.090 (0.864–1.376)	0.466
Hepatic failure	164	2.026 (1.426–2.879)	< 0.001	1.454 (0.990–2.135)	0.056
Tumor	754	1.171 (0.948–1.445)	0.143
Sepsis	3126	1.320 (0.849–2.050)	0.217
ARDS	2845	1.060 (0.8121–1.382)	0.670

Bold indicates statistically significant P values