Skip to main content
. 2023 Jun 29;14(28):7725–7732. doi: 10.1039/d3sc01997g

Association constants, Ka (M−1), for trans and cis isomers of templates Azo, mAzo, and ipAzo with α-, β-, and γ-CD.

K a a (M−1)
α-CD β-CD γ-CD
Trans-Azo 8100 ± 600 1800 ± 100 260 ± 30
Cis-Azo 500 ± 100 2800 ± 100 180 ± 20
Trans-mAzo 140 ± 40 420 ± 150 b
Cis-mAzo 50 ± 30 270 ± 100 b
Trans-ipAzo 170 ± 20 74 ± 9 b
Cis-ipAzo 33 ± 13 220 ± 80 2000 ± 300
a

Determined at 25 °C in 100 mM sodium phosphate buffer in D2O at pH 7.5.

b

The binding affinity was too weak to quantify.