Association constants, Ka (M−1), for trans and cis isomers of templates Azo, mAzo, and ipAzo with α-, β-, and γ-CD.
| K a a (M−1) | |||
|---|---|---|---|
| α-CD | β-CD | γ-CD | |
| Trans-Azo | 8100 ± 600 | 1800 ± 100 | 260 ± 30 |
| Cis-Azo | 500 ± 100 | 2800 ± 100 | 180 ± 20 |
| Trans-mAzo | 140 ± 40 | 420 ± 150 | b |
| Cis-mAzo | 50 ± 30 | 270 ± 100 | b |
| Trans-ipAzo | 170 ± 20 | 74 ± 9 | b |
| Cis-ipAzo | 33 ± 13 | 220 ± 80 | 2000 ± 300 |
Determined at 25 °C in 100 mM sodium phosphate buffer in D2O at pH 7.5.
The binding affinity was too weak to quantify.