Table 2.

Solutes in Plasma and Dialysate

		Conventional	Experimental
UN	plasma pre (mg/dl)	58 ± 22	62 ± 20
	plasma post (mg/dl)	16 ± 6	13 ± 6
	reduction ratio (%)	72 ± 4	80 ± 4 a
	removed in dialysate (mg)	16 ± 6 × 103	19 ± 6 × 103a
PCS	plasma pre (mg/dl)	5.6 ± 0.9	5.0 ± 0.7
	plasma post (mg/dl)	3.9 ± 0.9	2.6 ± 0.5 a
	% bound	94 ± 2	94 ± 1
	reduction ratio (%)	30 ± 14 b	48 ± 7 a,b
	removed in dialysate (mg)	208 ± 65	261 ± 37 a
IS	plasma pre (mg/dl)	3.8 ± 1.0	3.9 ± 1.2
	plasma post (mg/dl)	2.5 ± 0.7	1.8 ± 0.5 a
	% bound	92 ± 2	93 ± 1
	reduction ratio (%)	36 ± 10	53 ± 7 a,b
	removed in dialysate (mg)	177 ± 43	240 ± 54 a
KYNA	plasma pre (μg/dl)	17 ± 9	18 ± 5
	plasma post (μg/dl)	11 ± 4	7 ± 2
	% bound	90 ± 2	91 ± 2
	reduction ratio (%)	34 ± 10 b	58 ± 7 a
	removed in dialysate (mg)	1.2 ± 0.7	1.7 ± 0.6 a
Hippurate	plasma pre (mg/dl)	5.5 ± 3.5	7.4 ± 3.3
	plasma post (mg/dl)	1.8 ± 1.3	1.5 ± 0.6
	% bound	55 ± 4	56 ± 4
	reduction ratio (%)	67 ± 8 c	79 ± 4 a,c,d
	removed in dialysate (mg)	740 ± 521	1153 ± 398

Values are mean ± sd.

^a, p < 0.05 experimental vs conventional treatment. Significance of differences between different solutes is indicated for the reduction ratios only;

^b, p < 0.05 vs UN;

^c, p < 0.05 vs PCS;

^d, p < 0.05 vs IS. The reduction ratio is calculated as (plasma pre – plasma post)/plasma pre. Note: Conversion factors for units: Plasma UN in mg/dl to mmol/L, x0.357; plasma PCS in mg/dl to mmol/L, ×0.053; plasma IS in mg/dl to mmol/L, ×0.047; plasma KYNA in μg/dl to μmol/L, ×0.053; plasma Hippurate in mg/dl to mmol/L, ×0.056.

Abbreviations: UN, urea nitrogen; PCS, p-cresol-sulfate; IS, indoxyl sulfate; KYNA, kynurenic acid.