Figure 5.
Knockdown of ESM1 affects cell proliferation, migration, and apoptosis of SiHa and ME-180 cells. (A-D) ESM1 mRNA and protein expression assessed by (A, C) RT-qPCR and (B, D) western blotting in SiHa and ME-180 cells after transfected with siRNAs. (E-J) Cell proliferation experiment (E, F), Cell mobility assay (G, H), cell invasion assay (I, J), cell apoptosis assay (K, L) of SiHa or ME-180 cells transfected with siESM1, siVEGFα, or siNC for 72 h and 48 h, respectively. * P<0.05, ** P <0.01, *** P <0.001 (Mean ± SD, Student's t-test.).