Table 2.
The main diagnostic values of the FAM83 family proteins in solid tumors.
| FAM83 family proteins | Main diagnostic values in solid tumors |
|---|---|
| FAM83A | Highly expressed in lung cancer, HCC, breast cancer, pancreatic cancer, bladder cancer, and ovarian cancer. It can be effective marker of tumor progression and adverse clinical prognosis. |
| FAM83B | Highly expressed in breast cancer, bladder cancer, testicular cancer, ovarian cancer, thyroid cancer, and lung cancer. It can be effective marker of tumor progression and adverse clinical prognosis. |
| FAM83C | Highly expressed in lung cancer and GC. It can be effective marker of tumor progression and adverse clinical prognosis. |
| FAM83D | Highly expressed in breast cancer, GC and HCC. It can be effective marker of tumor progression. |
| FAM83E | Highly expressed in PDAC. |
| FAM83F | Highly expressed in LUAD. It can be effective marker of tumor progression and adverse clinical prognosis of patients with LUAD. |
| FAM83G | Highly expressed in HCC. It can be effective marker of tumor progression and adverse clinical prognosis of patients with HCC. |
| FAM83H | Highly expressed in PDAC and ovarian cancer. It can be effective marker of tumor progression and adverse clinical prognosis of patients with PDAC. |