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. 2023 Jun 26;14(10):1888–1903. doi: 10.7150/jca.83420

Table 2.

The main diagnostic values of the FAM83 family proteins in solid tumors.

FAM83 family proteins Main diagnostic values in solid tumors
FAM83A Highly expressed in lung cancer, HCC, breast cancer, pancreatic cancer, bladder cancer, and ovarian cancer. It can be effective marker of tumor progression and adverse clinical prognosis.
FAM83B Highly expressed in breast cancer, bladder cancer, testicular cancer, ovarian cancer, thyroid cancer, and lung cancer. It can be effective marker of tumor progression and adverse clinical prognosis.
FAM83C Highly expressed in lung cancer and GC. It can be effective marker of tumor progression and adverse clinical prognosis.
FAM83D Highly expressed in breast cancer, GC and HCC. It can be effective marker of tumor progression.
FAM83E Highly expressed in PDAC.
FAM83F Highly expressed in LUAD. It can be effective marker of tumor progression and adverse clinical prognosis of patients with LUAD.
FAM83G Highly expressed in HCC. It can be effective marker of tumor progression and adverse clinical prognosis of patients with HCC.
FAM83H Highly expressed in PDAC and ovarian cancer. It can be effective marker of tumor progression and adverse clinical prognosis of patients with PDAC.