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. 2023 Jun 26;14(10):1913–1919. doi: 10.7150/jca.84261

Table 2.

Association between IMDC severity and CRP levels before and after treatment

Characteristic N Initial CRP
Median (IQR)
p value N Post-treatment CRP
Median (IQR)
p value
Diarrhea grade 0.015 0.238
1-2 23 12.1 (5.3-31.4) 38 3.4 (1.0-7.6)
3-4 43 35.1 (9.6-69.0) 61 4.1 (1.3-15.1)
Colitis grade 0.013 0.183
1 19 17.1 (7.8-28.9) 23 2.6 (1.0-4.5)
2-4 30 49.0 (12.1-82.4) 52 4.4 (1.9-14.9)
Endoscopic presentation 0.016 0.397
Active inflammation (ulcer ± non-ulcer inflammation) 52 30.1 (9.1-72.4) 81 2.6 (1.0-9.1)
Normal 16 15.4 (5.9-23.8) 21 3.8 (1.3-14.2)

IMDC, immune-mediated diarrhea and colitis; CRP, C-reactive protein; IQR, interquartile range.

Mann-Whitney U test was used for analysis and reported as median and IQR.