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The precursors and active forms of MMP-9 and MMP-2 are increased by diabetes. The gelatinases (MMP-9 and MMP-2) were assessed by zymography in acrylamide gels copolymerized with gelatin (a), followed by densitometry analysis (b, c). Data in b and c were expressed as folds of change, with the BC group set to 1. Representative images and means ± SD of three independent samples, each one obtained from 2 or 3 tumors, are presented, **p ≤ 0.01; ***p < 0.001 versus BC
