Table 2.
Effects of AKG supplementation on the ileal morphology of piglets after 4 h LPS challenge
| Item | Saline | LPS | SEM | P-value | ||||
|---|---|---|---|---|---|---|---|---|
| CON | AKG | CON | AKG | Diet | LPS | Interaction | ||
| Villus height, μm | 225.24b | 417.95a | 171.24c | 223.14b | 8.681 | <0.01 | <0.01 | <0.01 |
| Villus area, μm | 91486.34c | 277997.12a | 47143.60d | 107962.11b | 9985.774 | <0.01 | <0.01 | <0.01 |
| Crypt depth, μm | 236.19b | 116.99c | 351.15a | 207.83b | 12.295 | <0.01 | <0.01 | 0.339 |
| VCR | 0.98b | 3.79a | 0.53c | 1.10b | 0.132 | <0.01 | <0.01 | <0.01 |
a,b,c,dLabeled means in a row without a common letter differ at P < 0.05.
Values are expressed as the mean ± standard error (n = 6).
CON, control; LPS, lipopolysaccharide; AKG, alpha-ketoglutarate. VCR, villus height/crypt depth ratio.