Table 4.

Effects of AKG supplementation on the relative mRNA levels of inflammatory cytokine in the ileal mucosa of piglets after 4 h LPS challenge

Item	Saline		LPS		SEM	P-value
	CON	AKG	CON	AKG		Diet	LPS	Interaction
IL-6	1.0000b	0.6337c	1.5510a	0.8357b	0.068	<0.01	<0.01	0.019
IL-1β	1.0000b	0.6761c	1.3178a	0.8938b	0.065	<0.01	0.001	0.452
IL-8	1.0000b	0.6507c	1.5083a	1.0225b	0.067	<0.01	<0.01	0.320
TNF-α	1.0000b	0.6715c	1.5525a	0.7280c	0.075	<0.01	<0.01	0.003
IL-10	1.0000b	1.4603a	0.3553c	0.9552b	0.088	<0.01	<0.01	0.436

^a,b,c,dLabeled means in a row without a common letter differ at P < 0.05.

Values are expressed as the mean ± standard error (n = 6).

IL, interleukin. CON, control; LPS, lipopolysaccharide; AKG, alpha-ketoglutarate.