Table 1. Baymer modeled 1KG private continental context mutations with extreme polymorphism probability differences.
Population Comparison | Context Mutation | ln(Poly. Prob. Fraction) | Poly. Prob. Fraction Overlap | Shift Difference | Shift Fraction Overlap | Population Specificity |
---|---|---|---|---|---|---|
European vs. African | TCC>Tabc | 0.291 | 0 | -0.174 | 1.4E-157 | European |
TCT>Tabc | 0.136 | 1.6E-18 | -0.116 | 8.5E-16 | European | |
GCAATTA>G | 0.569 | 4.7E-03 | -0.668 | 2.4E-03 | - | |
TATATATC>G | -0.660 | 7.2E-03 | 0.730 | 5.6E-03 | African | |
European vs. South Asian | TCC>Tabc | 0.112 | 1.2E-09 | -0.059 | 2.7E-03 | European |
TCT>Tabc | 0.063 | 5.0E-03 | -0.066 | 2.9E-03 | European | |
CTATA>T | -0.587 | 2.9E-03 | 0.493 | 7.3E-03 | South Asian | |
ATCTTC>G | -0.606 | 7.6E-03 | 0.668 | 5.4E-03 | - | |
European vs. East Asian | CCC>Tabc | 0.081 | 1.4E-03 | 0.075 | 6.6E-04 | - |
TCC>Tabc | 0.312 | 0 | -0.156 | 2.4E-97 | European | |
GCT>T | -0.064 | 5.7E-03 | 0.095 | 6.1E-05 | - | |
TCT>Tabc | 0.133 | 3.0E-19 | -0.102 | 9.6E-06 | European | |
GCAACCA>G | 1.056 | 5.3E-03 | -1.104 | 5.0E-03 | - | |
ATACCTC>A | -1.029 | 4.2E-03 | 0.830 | 5.0E-03 | East Asian | |
African vs. South Asian | TCC>Tabc | -0.179 | 1.7E-118 | 0.115 | 3.4E-12 | - |
CTATA>T | -0.507 | 6.1E-03 | 0.482 | 7.4E-03 | South Asian | |
CCCCCAG>G | -0.818 | 2.6E-03 | 0.767 | 2.7E-03 | - | |
TATATATC>G | 0.668 | 3.3E-03 | -0.738 | 2.2E-03 | African | |
African vs. East Asian | GCT>T | -0.063 | 9.1E-03 | 0.074 | 2.2E-03 | - |
CTCGCG>T | 1.240 | 2.8E-03 | -1.243 | 3.6E-03 | - | |
TAAAATA>T | -1.160 | 3.9E-03 | 1.135 | 4.8E-03 | - | |
ATACCTC>A | -1.061 | 4.6E-03 | 0.829 | 5.7E-03 | East Asian | |
TATATATC>G | 0.712 | 3.9E-04 | -0.748 | 1.3E-04 | African | |
East Asian vs. South Asian | TCC>Tabc | -0.200 | 2.4E-155 | 0.097 | 5.4E-05 | - |
CTATA>T | -0.519 | 5.3E-03 | 0.479 | 7.8E-03 | South Asian | |
CTCGCG>T | -1.244 | 2.0E-03 | 1.247 | 2.7E-03 | - | |
ATACCTC>A | 0.906 | 8.5E-03 | -0.819 | 9.1E-03 | East Asia | |
CCCCCAG>G | -0.819 | 3.8E-03 | 0.764 | 4.4E-03 | - |