Table 3.
The results of the pathomorphological examination of the studied hearts.
| Group / parameter | Control n = 10 |
FHT n = 17 |
HCM n = 13 |
p-values |
|---|---|---|---|---|
| Heart weight [g] median (min–max) | 15 (13–15) | 22.5 (18–24) | 34.5 (15–45) |
1p > 0.05 2p = 0.04 3p > 0.05 |
| Heart height [mm] median (min–max) | 38.2 (30.3–41.2) | 41.3 (36.6–53.6) | 50.2 (34.2–63.5) |
1p > 0.05 2p < 0.001 3p > 0.05 |
| Heart width [mm] mean ± SD | 25.8 ± 3.7 | 32.6 ± 3.3 | 34.2 ± 5.1 |
1p = 0.003 2p < 0.001 3p > 0.05 |
| Left atrial appendage height [mm] median (min–max) | 10.9 (8.2–13.2) | 16.0 (10–29.8) | 25.4 (15.3–38) |
1p > 0.05 2p < 0.001 3p > 0.05 |
| Left atrial appendage width [mm] median (min–max) | 10.4 (8.4–11.8) | 15.3 (12.5–16.9) | 19.9 (12.6–34.2) |
1p = 0.03 2p < 0.001 3p > 0.05 |
| Right atrial appendage height [mm] mean ± SD | 10.8 ± 1.7 | 12.9 ± 3.7 | 15.3 ± 2.9 |
1p > 0.05 2p = 0.004 3p > 0.05 |
| Right atrial appendage width [mm] mean ± SD | 9.5 ± 1.2 | 12.4 ± 3.1 | 13.7 ± 5.1 | p > 0.05 |
| LVW [mm] mean ± SD | 6.6 ± 0.7 | 6.9 ± 1.7 | 10.1 ± 1.6 |
1p > 0.05 2p < 0.001 3p < 0.001 |
| LVID [mm] median (min–max) |
6 (4.9–7.3) | 7.3 (4.9–13.2) | 9.4 (2.3–13.3) | p > 0.05 |
| IVS [mm] mean ± SD | 5.7 ± 0.7 | 6.0 ± 1.5 | 8.4 ± 1.0 |
1p > 0.05 2p < 0.001 3p < 0.001 |
| RVID [mm] mean ± SD | 7.0 ± 1.7 | 6.1 ± 3.2 | 5.5 ± 2.7 | p > 0.05 |
| RVW [mm] mean ± SD | 2.1 ± 0.5 | 2.9 ± 1.1 | 4.1 ± 1.4 |
1p > 0.05 2<0.001 3p = 0.03 |
| Heart surface [mm2] median (min–max) | 572.9 (478.8–745.2) |
586.0 (380.0–1069.1) |
852.6 (508.5–1326.4) |
1p > 0.05 2p = 0.01 3p = 0.01 |
| Left ventricle surface [mm2] median (min–max) | 373.6 (358.9–471.9) |
391.7 (284.8–680.9) |
611.9 (392.7–1043.2) |
1p > 0.05 2p = 0.001 3p = 0.003 |
| Left ventricular lumen surface [mm2] median (min–max) | 40.6 (17.1–46.7) | 38.0 (11.5–203.4) | 42.1 (7.0–166.9) | p > 0.05 |
| Left ventricular wall surface [mm2] median (min–max) | 328.7 (314.9–436.0) |
357.8 (236.6–477.5) |
582.4 (380.3–986.0) |
1p > 0.05 2p = 0.002 3p < 0.001 |
| Right ventricular lumen surface [mm2] median (min–max) | 69.7 (63.3–98.2) | 74.6 (9.4–159.1) | 46.1 (20.7–261.2) | p > 0.05 |
IVS: interventricular septum diameter; LVID: left ventricular internal diameter; LVW: left ventricular wall diameter; RVID: right ventricular internal diameter; RVW: right ventricular wall diameter; parametric data presented as mean ± SD; non-parametric data presented as median (min–max); single p-value >0.05 presented in parameters without significant differences between the groups; particular p-values presented for the comparison of: control and FHT group (1), control and HCM group (2) and FHT and HCM group (3) in parameters with significant differences between the groups; the significance level set at p ≤ 0.05; the significant p-values marked bold.