Table 3.
Clinical characteristics of pituitary adenoma patients with positive or negative family cancer history
| Positive family cancer history | Negative family cancer history | p value | |
|---|---|---|---|
| N | 495 (46.6%) | 567 (53.4%) | |
| Male sex | 164 (33.1%) | 222 (39.2%) | 0.042 |
| Age (yrs.) | |||
| Actual age | 49.1 ± 16.1 | 51.9 ± 16.6 | 0.009 |
| At diagnosis of PA | 43.6 ± 15.9 | 46.0 ± 16.4 | 0.015 |
| Type of PA | |||
| Acromegaly | 96 (19.4%) | 124 (21.9%) | 0.056 |
| Prolactinoma | 192 (38.8%) | 180 (31.7%) | |
| NFPA | 207 (41.8%) | 263 (46.4%) | |
| Hypopituitarism | 114 (23.0%) | 154 (27.2%) | 0.174 |
PA pituitary adenoma, NFPA nonfunctioning pituitary adenoma
*Results are presented as counts (%, where appropriate), or mean ± standard deviation