Fig. 1.

miR-196-5p expression is reduced in HCC. a, b Expression of miR-196-5p was measured in HCC tumors and adjacent healthy tissue, with U6 used for normalization. c miR-196-5p expression in patients with or without vascular invasion. d The expression of miR-196-5p in large and small HCC tissues. e The expression of miR-196-5p in HCC tissues of TNM stages III–IV vs. I–II. The expression of miR-196-5p in HCC tumors with early and late recurrence (*p < 0.05, **p < 0.01, ***p < 0.001) Abbreviations: VI, vascular invasion; T, tumor size; Rec, recurrence