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. 2019 Nov 12;10(4-6):177–189. doi: 10.1007/s12672-019-00370-5

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Fig. 3 — miR-196-5p expression disrupts the migration and invasion abilities of HCC cells. a, b Transwell assays revealed that SMMC cell invasion potential was impaired upon miR-196-5p overexpression, whereas downregulation of this miRNA in HCCLM3 cells had the opposite effect, n = 5. c Murine lung tissue samples were collected and H&E-stained following the intravenous injection of 1x10⁶ SMMC-7721 cells (Scale bar = 500 μm). d Lung metastatic nodule counts (n = 9). e Murine survival curves in mice following injection with SMMC-LV-GFP or SMMC-LV-miR-196-5p cells. A two-sided log-rank test was used to assess significance (*p < 0.05, **p < 0.01, ***p < 0.001).