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. 2023 Jul 19;9(29):eadg2697. doi: 10.1126/sciadv.adg2697

Fig. 9. The combination of anti-CD47 antibody and DL@NP-M-M2pep promotes antitumor efficacy in carcinogen-induced orthotopic HCC mice.

Fig. 9.

(A) Tumor induction and treatment scheme. (B) The representative images of HCC with different treatments. (C) Tumor weight after subtracting liver weight of healthy mice (n = 5). (D) Animal survival (n = 10). (E) Flow cytometric analysis of immune cells (n = 5) (figs. S14 to S19). MHC, major histocompatibility complex. (F) The average number of apoptotic cells per high-power field was detected by TUNEL staining and analyzed by ImageJ (scale bar, 50 μm; n = 3) (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, and ns to PBS).