Table 1.
Baseline physical, biochemical and demographic characteristics of study participants at W2 (2001–2004) for the entire cohort, and in men who developed prostate, lung and colorectal cancer
| Entire sample | Prostate cancer | Lung cancer | Colorectal cancer | ||||
|---|---|---|---|---|---|---|---|
| No | Yes | No | Yes | No | Yes | ||
| n = 3690 | n = 3342 | n = 348 | n = 3562 | n = 107 | n = 3436 | n = 137 | |
| Variable | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD |
| Age (year) | 77.0 ± 3.6 | 77.0 ± 3.6 | 76.8 ± 3.6 | 76.9 ± 3.6 | 77.5 ± 3.1 | 76.9 ± 3.6* | 77.9 ± 3.8* |
| BMI (kg/m2) | 26.5 ± 3.6 | 26.5 ± 3.6 | 26.5 ± 3.5 | 26.5 ± 3.6 | 26.1 ± 3.6 | 26.5 ± 3.6 | 26.4 ± 3.6 |
| Total T (nmol/l) | 13.1 ± 4.9 | 13.1 ± 4.9 | 13.2 ± 4.4 | 13.1 ± 4.9 | 13.9 ± 5.4 | 13.1 ± 4.9 | 12.7 ± 4.4 |
| cFT (pmol/l) | 185 ± 55 | 185 ± 55 | 187 ± 50 | 185 ± 54 | 193 ± 61 | 185 ± 55 | 181 ± 50 |
| DHT (nmol/l) | 1.44 ± 0.7 | 1.43 ± 0.7 | 1.47 ± 0.7 | 1.43 ± 0.7 | 1.55 ± 0.8 | 1.44 ± 0.7 | 1.39 ± 0.7 |
| E2 (pmol/l) | 73.4 ± 29.1 | 73.3 ± 29.2 | 74.5 ± 28.0 | 73.4 ± 29.0 | 73.9 ± 30.7 | 73.3 ± 29.0 | 75.9 ± 32.5 |
| LH (IU/l) | 5.78 ± 5.27 | 5.84 ± 5.35* | 5.19 ± 4.43* | 5.76 ± 5.18 | 6.68 ± 5.13 | 5.75 ± 5.16 | 6.22 ± 5.48 |
| SHBG (nmol/l) | 42.4 ± 16.7 | 42.5 ± 16.9 | 42.0 ± 15.4 | 42.4 ± 16.8 | 44.4 ± 16.6 | 42.5 ± 16.9 | 42.9 ± 15.3 |
| Smoking, n (%) | |||||||
| Never | 1226 (33.2) | 1096 (32.8) | 130 (37.4) | 1222 (34.3)* | 3 (2.8)* | 1162 (33.8)* | 34 (33.5)a |
| Ex | 2259 (61.2) | 2056 (61.5) | 203 (58.3) | 2155 (60.5)* | 86 (80.4)* | 2077 (60.5)* | 100 (72.5)* |
| Current | 204 (5.5) | 189 (5.7) | 15 (4.3) | 184 (5.17)* | 18 (16.8)* | 196 (5.7)* | 4 (2.9)* |
| Alcohol (drinks/week), n (%) | |||||||
| Non-drinker | 517 (14.7) | 473 (14.9) | 44 (13.4) | 505 (14.9) | 9 (8.7) | 473 (14.8) | 21 (16.0) |
| <15 | 2353 (67.0) | 2130 (66.9) | 221 (67.4) | 2274 (67.1) | 68 (66.0) | 2188 (66.9) | 87 (66.4) |
| 15–28 | 486 (13.8) | 437 (13.7) | 49 (14.9) | 462 (13.6) | 20 (19.4) | 451 (13.8) | 16 (12.2) |
| >28 | 157 (4.5) | 143 (4.5) | 157 (4.5) | 149 (4.4) | 6 (5.8) | 146 (4.5) | 7 (5.3) |
| Vigorous physical activity, n (%) | |||||||
| ≥150 min/week | 840 (22.8) | 745 (22.3)* | 95 (27.3)* | 818 (23.0) | 18 (17.0) | 781 (22.8) | 30 (21.7) |
| Diabetes mellitus | 530 (14.4) | 491 (14.7) | 39 (11.2) | 513 (14.4) | 13 (12.2) | 493 (14.4) | 24 (17.4) |
p values are for t tests or Pearson’s χ 2 test as appropriate
*p value <0.05