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. 2017 Feb 23;8(2):119–126. doi: 10.1007/s12672-017-0287-4

Table 4.

Competing-risks proportional hazards models for the association of hormone variables with the incidence of lung cancer

Model 1 Model 2
SHR (95% CI) p value SHR (95% CI) p value
T, nmol/l 1.24 (1.02, 1.50) 0.029 1.30 (1.06, 1.60) 0.012
cFT, pmol/l 1.24 (1.01, 1.52) 0.041 1.30 (1.04, 1.62) 0.022
DHT, nmol/l 1.24 (1.04, 1.49) 0.017 1.29 (1.08, 1.54) 0.004
E2, pmol/l 1.05 (0.86, 1.29) 0.619 1.07 (0.87, 1.30) 0.531
Log LH, IU/l 1.04 (0.83, 1.29) 0.753 1.04 (0.83, 1.29) 0.757
SHBG, nmol/l 1.08 (0.92, 1.27) 0.351 1.10 (0.93, 1.31) 0.276

Estimates represent subhazard ratios and 95% CIs for each SD increase in hormone level. Model 1 includes adjustments for age, BMI and smoking status. Model 2 includes adjustments for age, BMI, smoking status, physical activity, duration of smoking, smoking exposure (greatest number of cigarettes smoked for ≥1 year), alcohol, diabetes, HDL, TG and history of prevalent cancer