Table 2.
Study group genotypes, descriptions of genetic modifications and abbreviations of genotype, where ‘+’ indicates presence of Pten mutations or TgFSH overexpression and ‘−’ indicates the absence of Pten mutations or TgFSH overexpression
| Abbreviation | TgFSH | PtenGC+/− | PtenGC−/− | Pten+/− | |
|---|---|---|---|---|---|
| AMH. Cre model (ovary specific) | |||||
| Non-Tg control | C | − | − | − | − |
| Non-Tg PtenGC+/− | PtenGC+/− | − | + | − | − |
| Non-Tg PtenGC−/− | PtenGC−/− | − | − | + | − |
| TgFSH control | F | + | − | − | − |
| TgFSH PtenGC+/− | FPtenGC+/− | + | + | − | − |
| TgFSH PtenGC−/− | FPtenGC−/− | + | − | + | − |
| Sox2. Cre model (global) | |||||
| Non-Tg Pten+/− | Pten+/− | − | − | − | + |
| TgFSH Pten+/− | FPten+/− | + | − | − | + |