Table 2.

Univariate and multivariate analyses of 1-, 2-year and overall survival for synchronous metastases, ≥2 affected organs and ≥4 metastases

	1-Year survival			2-Year survival			Overall survival
	HR	95 % CI	p	HR	95 % CI	p	HR	95 % CI	p
Univariate analysis
Synchronous metastases	.94	.87–1.01	0.096	1.86	1.03–3.34	0.039	1.66	1.02–2.75	0.048
≥2 Affected organs	3.52	2.025–6.134	<0.001	2.95	1.83–4.74	<0.001	2.82	1.82–4.35	<0.001
≥4 Metastases	3.30	1.61–6.78	0.001	3.38	1.85–6.2	<0.001	3.26	1.95–5.45	<0.001
Multivariate analysis
Synchronous metastases	.94	.87–1.01	0.101	1.85	1.02–2.36	0.044	1.66	.99–2.8	0.055
≥2 Affected organs	2.80	1.46–5.35	0.002	2.19	1.27–3.77	0.005	2.07	1.2–3.42	0.005
≥4 Metastases	1.80	.76–4.09	0.189	2.15	1.08–4.27	0.029	2.19	1.22–3.94	0.009