Table 2.
Clinical features of patients with thymic carcinoid (TC) tumors in patients with multiple endocrine neoplasia type 1 (MEN1)
Case | Age at diagnosis of MEN1 (years) | Age at diagnosis of TC tumor (years) | MEN1 features | Symptoms | Tumor size (cm) |
---|---|---|---|---|---|
1 | 53 | 55 | PHP/AA | Chest pain/dyspnea | 10 × 10 × 3 |
2 | 36 | 36 | PHP/gastrinoma | Thymic resection at the time of parathyroidectomy | 9 × 1.5 × 1 |
3 | 47 | 39 | PHP/NF NET/AA | Screening (chest x-ray) | 5.5 × 1.5 × 1 |
4 | 31 | 32 | PHP/insulinoma | Screening (chest-x-ray) | 11 × 6 × 7 |
5 | 27 | 41 | PHP | Chest pain | 7 × 6 × 4 |
6 | 43 | 65 | PHP/VIPoma/ZE/AA | Chest pain | 8 × 7.5 × 5 |
7 | 29 | 33 | PHP/insulinoma/AA/PRL | Chest pain | 5.5 |
PHP primary hyperparathyroidism, AA adrenal adenoma, NF NET nonfunctional neuroendocrine tumor, ZES Zollinger Ellison syndrome, PRL prolactinoma