Table 2.
Toxicity of interferon-α treatment
| Toxicity | Grade 1 | Grade 2 | Grade 3–4 | All grades |
|---|---|---|---|---|
| n (%) | n (%) | n (%) | n (%) | |
| Asthenia | 5 (36%) | 3 (21%) | 2 (14%) | 10 (71%) |
| Myalgia | 3 (21%) | None | None | 3 (21%) |
| Diarrhea | 1 (7%) | 2 (14%) | None | 3 (21%) |
| Anemia | 4 (29%) | 1 (7%) | None | 5 (36%) |
| Neutropenia | 2 (14%) | 2 (14%) | 2 (14%) | 6 (42%) |
| Lymphopenia | 5 (36%) | 1 (7%) | 1 (7%) | 7 (50%) |
| Thrombopenia | 5 (36%) | None | None | 5 (36%) |
| Thyroid dysfunction | None | 1 (7%) | None | 1 (7%) |
| AST/ALT elevation | 3 (21%) | 1 (7%) | None | 4 (28%) |
| Other toxicity (n=) | Alopecia G1(1) G2(1), hypertension G1(1) G3(1), weight loss G2 (2), anorexia G2 (1), hypersomnia G2 (1), depression G1 (1), skin toxicity G1 and G21) | 10 (71%) | ||
G grade