Table 1.
Demographic, genetic, and MEN1-related features of patients with MEN1 with thymic carcinoids (n = 9)
| Characteristic | Value | |
|---|---|---|
| Sex n | Male | 6 |
| Female | 3 | |
| Criteria used to diagnose MEN1 (clinical or genetic)a n | PHPT and PIT | 3 |
| PHPT and PNET | 2 | |
| PHPT, PNET, and PIT | 3 | |
| Genetic criteria | 1 | |
| MEN1-related disease penetrance n | PHPT | 8 |
| PNET | 5 | |
| PIT | 6 | |
| Familial MEN1 n | Yes | 5 |
| No | 4 | |
| Age at date of diagnosis (years)b mean (SD), range | Thymic carcinoid | 38.6 (8.8), 22–47 |
| PNET | 42.4 (6.8), 32–48 | |
| PHPT | 37.3 (10.1), 20–48 | |
| PIT tumor | 47.8 (3.9), 44–55 | |
| Time to metachronous metastasis from thymic carcinoid diagnosis (years) median, range | 4.4, 0.3–15.8 | |
| Follow-up (months) mean (SD), range | 55.3 (47.4), 1–178 | |
aAccording to Thakker et al.
bData only for cases with the respective disease