Fig. 1.

The expression of miR-15b and IGF1R was decreased in glioblastoma tissues. The expression of miR-15b (a) and IGF1R (b) in 40 cases of glioblastoma tissues and normal tissues was detected using qRT-PCR assay (c). The expression of miR-15b and IGF1R in 40 cases of glioblastoma tissues and normal tissues was detected using RT-PCR assay. The expression of miR-15b in glioblastoma tumor tissues was significantly lower than that in paired normal tissues. d The overall survival rate of glioblastoma patients with low miR-15b expression was much lower than that of glioblastoma patients with high miR-15b expression. *p < 0.001 vs. normal control