Table 5.

Gene symbols and beta coefficients of gene subsets determined by LASSO analysis without or with regard to sex steroid receptors status

PFS		OS
Gene symbol	β	Gene symbol	β
CYP2E	− 0.16	CYP2E	− 0.08
PDE1A	0.67	PDE1A	0.03
PDE4A	− 1.85	PDE4A	− 0.18
		PDE1B	0.12
		ADORA1	0.01
PFS ER−		PFS PR−
Gene symbol	β	Gene symbol	β
PDE4A	1.24	PDE4A	− 0.81
CACNA1S	0.07	CACNA1S	0.47
RYR1	− 0.56	RYR1	− 0.22
PDE1A	− 0.33	PDE1C	0.03
PDE4B	− 0.59	SPECC1L	− 0.76
XDH	− 0.13
OS ER−		OS PR−
Gene symbol	β	Gene symbol	β
PDE4A	− 0.21	PDE4A	− 1.03
CACNA1S	0.20	CACNA1S	0.76
PDE1A	1.06	ADORA1	0.08
RYR1	− 0.83	SPECC1L	− 0.52
XDH	− 0.05

PFS and OS models (n = 247) without regard to sex steroid receptor status. PFS models with regard to either ER− (n = 101) or PR− (n = 96) carcinomas. OS models with regard to either ER− (n = 101) or PR− (n = 96) carcinomas