Table 4.

Reclassification Table Using Category‐Free NRI. Model With Protein Score in Addition to Baseline Variables

	All	Reclassified upwards n (proportion)	Reclassified downwards N (proportion)	NRI
Number of cases	126	88.96 (0.71)	37.04 (0.29)	Among cases	0.41 (0.25–0.57)
Number of controls	249	92.88 (0.37)	153.88 (0.62)	Among controls	0.25 (0.13–0.37)
Overall NRI (CI)					0.66 (0.46–0.86)

Net reclassification index (NRI) of cases is greater than NRI of controls. This suggests that addition of the protein score helps increase predicted risk for those with cases more than it decreases predicted risk for controls.