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. 2023 Mar 23;34(7):1264–1278. doi: 10.1681/ASN.0000000000000124

Table 5.

Independent clinical characteristics associated with nephron number in retained kidney in the combined sample of both kidney donors and patients with tumor

Characteristic All Donors and Tumor Patients (N=4374) Only Donors and Tumor Patients with Measured Cortical Volume (N=3513)
Estimate P Value Estimate P Value
Age per 10 yr (up to age 70 yr) −38,473a <0.0001a −43,007a <0.0001a
Age, per 10 yrs (>70 yr) −111,786a <0.0001a −94,378a 0.01a
Male 56,546a 0.002a 52,230a 0.01a
Height per SD 53,663a <0.0001a 57,402a <0.0001a
BMI per SD 13,292 0.052 13,006 0.11
Hypertension −54,958a 0.001a −45,839a 0.02a
Diabetes −48,776 0.14 −18,848 0.70
Family history of ESKD −80,394a <0.0001a −85,142a <0.0001a
eGFR per SD 74,558a <0.0001a 72,255a <0.0001a
24 h urine protein >165 mg −52,027a 0.007a −43,588 0.07
Patients with tumor versus donors −3354 0.88 −32,258 0.25

BMI, body mass index.

The mean SD across both populations was used (9.76 cm for height, 5.7 kg/m2 for body mass index, 21.6 ml/min/1.73m2 for eGFR).