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. 2023 Mar 23;34(7):1264–1278. doi: 10.1681/ASN.0000000000000124

Table 6.

Age-based thresholds used to define low nephron number per kidney based on a combined sample (N=1240 donors and N=327 patients with tumor) after excluding those with diabetes, hypertension, family history of ESKD, 24 hours urine protein >500 mg/d, eGFR <60 ml/min per 1.73 m2 for age <60 years, and eGFR <45 ml/min per 1.73 m2 for age ≥60 years

Age (yr) Male Female
n 5th Percentiles 10th Percentiles n 5th Percentiles 10th Percentiles
Threshold n (%) Abnormal Threshold n (%) Abnormal Threshold n (%) Abnormal Threshold n (%) Abnormal
18–39 198 <832,551 10 (5.1) <868,983 20 (10.1) 257 <597,963 13 (5.1) <718,571 26 (10.1)
40–49 162 <685,956 9 (5.6) <765,753 17 (10.5) 276 <574,069 14 (5.1) <688,871 28 (10.1)
50–59 162 <681,376 9 (5.6) <739,822 17 (10.5) 229 <542,527 12 (5.2) <658,520 23 (10.0)
60–69 91 <621,889 5 (5.5) <672,435 9 (9.9) 112 <483,515 6 (5.4) <539,805 12 (10.7)
70+ 49 <553,210 3 (6.1) <575,894 5 (10.2) 31 <430,338 2 (6.5) <483,885 4 (12.9)