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. 2023 Apr 5;34(7):1279–1291. doi: 10.1681/ASN.0000000000000141

Figure 4.

Figure 4

Bulk RNA-seq displayed modest correlation with proteomics. (A) Correlation between kidney bulk RNA-seq and proteomics using all samples. (B) Correlation between bulk RNA-seq and proteomics using a representative sample. (C) Correlation of MMP7 expression between RNA and protein, with Pearson R of 0.64. (D) Correlation between MMP7 expression examined by bulk RNA-seq and eGFR, with Pearson R of −0.53. (E) Correlation between MMP7 expression examined by bulk RNA-seq and interstitial fibrosis, with Pearson R of 0.52. (F) Box plots showing MMP7 expression examined by bulk RNA-seq in DKD and control subjects. P values were calculated with the Wilcoxon rank-sum test (for two group comparison). Figure 4 can be viewed in color online at www.jasn.org.