Table 1.
All-age meningitis incidence and mortality counts and age-standardised rates in 1990 and 2019, and percentage change in deaths, cases, and age-standardised incidence and mortality rates between 1990 and 2019, by SDI quintile, globally, and for the seven GBD super-regions and 21 GBD regions
|
Mortality |
Incidence |
Percentage change (1990–2019) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1990 counts | Age- standardised rate (per 100 000), 1990 | 2019 counts | Age- standardised rate (per 100 000), 2019 | 1990 counts | Age- standardised rate (per 100 000), 1990 | 2019 counts | Age- standardised rate (per 100 000), 2019 | Mortality | Age- standardised mortality rate | Incidence | Age- standardised incidence rate | ||
| Global | 433 000 (376 000 to 494 000) | 7·5 (6·6 to 8·4) | 236 000 (204 000 to 277 000) | 3·3 (2·8 to 3·9) | 3 290 000 (2 700 000 to 4 000 000) | 55·3 (45·9 to 66·7) | 2 510 000 (2 110 000 to 2 990 000) | 35·4 (29·6 to 42·5) | −45·4% (−53·5 to −35·8) | −56·0% (−62·5 to −48·3) | −23·8% (−26·5 to −20·4) | −35·9% (−37·0 to −34·6) | |
| Low SDI | 164 000 (137 000 to 196 000) | 24·8 (21·5 to 28·5) | 129 000 (106 000 to 157 000) | 11·2 (9·6 to 13·2) | 1 050 000 (864 000 to 1 280 000) | 145·4 (125·0 to 168·7) | 1 100 000 (914 000 to 1 330 000) | 82·3 (70·3 to 96·0) | −21·4% (−35·5 to −3·2) | −54·7% (−61·8 to −46·1) | 4·8% (2·0 to 7·9) | −43·4% (−44·4 to −42·6) | |
| Low-middle SDI | 148 000 (129 000 to 170 000) | 11·7 (10·5 to 13·2) | 65 800 (57 800 to 75 400) | 4·1 (3·6 to 4·6) | 1 070 000 (876 000 to 1 310 000) | 77·1 (64·8 to 91·4) | 725 000 (606 000 to 860 000) | 42·1 (35·4 to 50·0) | −55·5% (−62·5 to −47·2) | −65·3% (−70·2 to −59·7) | −32·4% (−35·7 to −28·3) | −45·4% (−46·7 to −43·8) | |
| Middle SDI | 86 200 (76 800 to 96 700) | 4·8 (4·3 to 5·4) | 29 400 (26 300 to 33 100) | 1·4 (1·2 to 1·6) | 715 000 (573 000 to 890 000) | 37·7 (30·8 to 46·3) | 425 000 (349 000 to 508 000) | 20·5 (16·8 to 24·7) | −65·9% (−70·8 to −59·8) | −71·6% (−75·5 to −66·8) | −40·5% (−44·4 to −35·3) | −45·6% (−47·7 to −43·0) | |
| High-middle SDI | 27 400 (25 000 to 30 000) | 2·6 (2·4 to 2·8) | 8520 (7840 to 9170) | 0·6 (0·6 to 0·7) | 306 000 (250 000 to 368 000) | 28·2 (23·0 to 34·2) | 166 000 (135 000 to 197 000) | 14·9 (12·0 to 18·0) | −68·9% (−72·8 to −64·8) | −76·6% (−79·7 to −73·2) | −45·9% (−49·5 to −41·4) | −47·0% (−49·6 to −44·1) | |
| High SDI | 6590 (6370 to 6810) | 0·8 (0·8 to 0·8) | 3300 (3090 to 3480) | 0·3 (0·2 to 0·3) | 147 000 (118 000 to 178 000) | 20·7 (16·5 to 25·2) | 91 800 (74 600 to 110 000) | 11·1 (8·9 to 13·5) | −49·9% (−52·4 to −47·5) | −68·8% (−70·5 to −67·2) | −37·5% (−41·5 to −32·3) | −46·2% (−48·2 to −43·5) | |
| Central Europe, eastern Europe, and central Asia | 8190 (7840 to 8550) | 2·2 (2·1 to 2·3) | 2700 (2440 to 2960) | 0·6 (0·6 to 0·7) | 130 000 (107 000 to 155 000) | 34·3 (28·3 to 40·7) | 70 800 (57 000 to 86 000) | 20·9 (16·6 to 25·6) | −67·0% (−70·3 to −63·3) | −71·4% (−74·5 to −67·9) | −45·7% (−48·6 to −42·5) | −39·2% (−43·1 to −35·5) | |
| Central Asia | 3030 (2790 to 3290) | 3·7 (3·5 to 4·0) | 638 (552 to 752) | 0·7 (0·6 to 0·8) | 41 100 (34 500 to 48 400) | 49·9 (42·2 to 58·6) | 27 500 (22 000 to 33 800) | 28·9 (23·1 to 35·6) | −79·0% (−82·2 to −74·7) | −81·2% (−83·9 to −77·5) | −33·2% (−39·2 to −27·6) | −42·1% (−47·0 to −37·4) | |
| Central Europe | 1740 (1670 to 1830) | 1·6 (1·6 to 1·7) | 421 (357 to 484) | 0·3 (0·3 to 0·3) | 22 600 (18 400 to 27 100) | 21·5 (17·5 to 25·9) | 10 300 (8220 to 12 300) | 12·2 (9·6 to 15·1) | −75·8% (−79·6 to −71·9) | −81·7% (−84·8 to −78·5) | −54·6% (−57·2 to −50·9) | −43·2% (−46·7 to −39·7) | |
| Eastern Europe | 3420 (3280 to 3570) | 1·7 (1·6 to 1·8) | 1640 (1480 to 1800) | 0·7 (0·6 to 0·8) | 66 700 (54 000 to 79 800) | 34·5 (27·8 to 41·6) | 33 000 (26 700 to 39 800) | 19·9 (15·7 to 24·4) | −52·0% (−57·3 to −46·7) | −58·5% (−62·9 to −54·0) | −50·5% (−53·2 to −47·4) | −42·5% (−46·0 to −38·7) | |
| High income | 7690 (7460 to 7930) | 0·9 (0·9 to 0·9) | 3820 (3570 to 4010) | 0·3 (0·3 to 0·3) | 164 000 (132 000 to 200 000) | 21·3 (17·0 to 25·9) | 96 000 (78 200 to 114 000) | 10·8 (8·7 to 13·1) | −50·3% (−52·8 to −48·2) | −68·9% (−70·7 to −67·3) | −41·5% (−45·2 to −37·0) | −49·1% (−51·2 to −46·5) | |
| Australasia | 125 (117 to 134) | 0·7 (0·6 to 0·7) | 59 (54 to 64) | 0·2 (0·2 to 0·2) | 4460 (3560 to 5500) | 25·1 (19·7 to 31·1) | 3490 (2790 to 4280) | 15·3 (11·9 to 19·2) | −53·0% (−57·6 to −48·1) | −72·1% (−75·5 to −68·5) | −21·7% (−26·4 to −16·1) | −39·3% (−43·5 to −34·9) | |
| High-income Asia Pacific | 1220 (1170 to 1280) | 0·8 (0·7 to 0·8) | 491 (427 to 531) | 0·1 (0·1 to 0·1) | 45 600 (35 500 to 57 300) | 31·8 (24·8 to 39·9) | 27 700 (22 200 to 33 600) | 21·2 (16·7 to 26·5) | −59·9% (−64·6 to −56·6) | −82·5% (−83·9 to −81·0) | −39·3% (−44·7 to −32·3) | −33·3% (−38·0 to −28·0) | |
| High-income North America | 1960 (1870 to 2080) | 0·7 (0·7 to 0·7) | 1240 (1170 to 1280) | 0·3 (0·3 to 0·3) | 29 800 (23 500 to 36 700) | 11·6 (9·1 to 14·5) | 16 300 (13 600 to 19 300) | 4·4 (3·7 to 5·2) | −37·0% (−40·7 to −33·9) | −58·9% (−61·5 to −56·7) | −45·2% (−52·5 to −36·4) | −61·9% (−66·4 to −56·1) | |
| Southern Latin America | 1190 (1140 to 1250) | 2·5 (2·3 to 2·6) | 580 (524 to 631) | 0·8 (0·7 to 0·9) | 11 400 (9500 to 13 700) | 22·7 (18·9 to 27·0) | 6780 (5550 to 8200) | 11·4 (9·2 to 13·9) | −51·4% (−56·3 to −46·0) | −66·8% (−70·4 to −63·0) | −40·7% (−44·7 to −36·4) | −49·9% (−52·9 to −46·7) | |
| Western Europe | 3180 (3080 to 3300) | 0·8 (0·8 to 0·9) | 1450 (1350 to 1550) | 0·2 (0·2 to 0·3) | 72 900 (59 400 to 87 100) | 23·8 (19·3 to 28·9) | 41 700 (34 000 to 49 600) | 12·5 (10·0 to 15·2) | −54·3% (−57·1 to −51·7) | −71·4% (−73·5 to −69·5) | −42·7% (−45·3 to −39·7) | −47·4% (−49·2 to −45·4) | |
| Latin America and Caribbean | 18 100 (16 700 to 19 600) | 4·1 (3·9 to 4·4) | 5560 (4720 to 6510) | 1·0 (0·9 to 1·2) | 140 000 (115 000 to 166 000) | 31·2 (25·9 to 36·5) | 93 000 (76 000 to 111 000) | 16·8 (13·7 to 20·0) | −69·2% (−74·8 to −63·0) | −75·2% (−79·7 to −70·3) | −33·5% (−39·8 to −25·8) | −46·3% (−49·9 to −42·3) | |
| Andean Latin America | 1320 (1150 to 1530) | 2·9 (2·6 to 3·4) | 395 (314 to 494) | 0·6 (0·5 to 0·8) | 7020 (5830 to 8360) | 14·7 (12·5 to 17·1) | 4400 (3590 to 5270) | 6·9 (5·7 to 8·3) | −70·0% (−77·4 to −60·7) | −77·9% (−83·2 to −71·4) | −37·3% (−42·5 to −31·8) | −52·7% (−56·2 to −48·9) | |
| Caribbean | 3470 (2930 to 4080) | 8·9 (7·6 to 10·4) | 1420 (1080 to 1860) | 3·4 (2·5 to 4·5) | 14 200 (12 000 to 16 600) | 36·3 (31·2 to 42·0) | 10 000 (8390 to 11 700) | 23·4 (19·4 to 27·6) | −59·0% (−70·7 to −43·6) | −62·1% (−73·2 to −47·6) | −29·3% (−32·8 to −25·5) | −35·6% (−39·0 to −32·5) | |
| Central Latin America | 4720 (4400 to 5070) | 2·6 (2·4 to 2·7) | 1670 (1370 to 2030) | 0·7 (0·6 to 0·9) | 37 300 (30 000 to 45 400) | 18·8 (15·6 to 22·5) | 19 900 (16 000 to 24 200) | 8·4 (6·7 to 10·2) | −64·6% (−71·9 to −56·2) | −72·9% (−78·4 to −66·5) | −46·6% (−51·1 to −41·1) | −55·4% (−58·1 to −52·6) | |
| Tropical Latin America | 8550 (7700 to 9660) | 5·3 (4·8 to 5·9) | 2070 (1870 to 2290) | 1·0 (0·9 to 1·1) | 81 500 (66 200 to 96 600) | 48·7 (40·1 to 57·4) | 58 700 (47 800 to 70 600) | 28·1 (22·8 to 34·0) | −75·7% (−79·4 to −71·7) | −80·8% (−83·7 to −77·6) | −28·0% (−36·3 to −18·3) | −42·4% (−47·9 to −36·7) | |
| North Africa and Middle East | 17 500 (14 400 to 21 500) | 4·2 (3·6 to 5·1) | 6280 (5330 to 7400) | 1·2 (1·0 to 1·4) | 143 000 (118 000 to 171 000) | 35·7 (30·5 to 41·2) | 129 000 (107 000 to 153 000) | 22·5 (18·9 to 26·4) | −64·1% (−72·2 to −54·5) | −71·6% (−77·1 to −64·9) | −9·9% (−16·3 to −1·9) | −37·0% (−39·9 to −33·9) | |
| South Asia | 131 000 (113 000 to 150 000) | 11·2 (10·0 to 12·5) | 55 500 (48 400 to 64 400) | 3·5 (3·0 to 4·0) | 1 150 000 (935 000 to 1 410 000) | 85·9 (71·6 to 103·0) | 742 000 (610 000 to 883 000) | 43·6 (36·2 to 52·3) | −57·5% (−65·0 to −49·0) | −69·0% (−74·0 to −63·3) | −35·3% (−38·7 to −31·2) | −49·2% (−50·7 to −47·5) | |
| Southeast Asia, east Asia, and Oceania | 76 800 (65 800 to 88 900) | 4·5 (3·9 to 5·2) | 18 200 (16 300 to 20 500) | 1·0 (0·9 to 1·2) | 452 000 (357 000 to 575 000) | 25·7 (20·4 to 32·6) | 177 000 (147 000 to 212 000) | 10·9 (8·8 to 13·3) | −76·3% (−80·3 to −71·7) | −77·4% (−81·2 to −73·2) | −60·9% (−63·5 to −57·6) | −57·6% (−59·3 to −55·3) | |
| East Asia | 38 600 (33 800 to 43 700) | 3·4 (3·0 to 3·8) | 6790 (5940 to 7680) | 0·5 (0·5 to 0·6) | 234 000 (182 000 to 302 000) | 19·7 (15·4 to 25·3) | 50 700 (41 600 to 60 300) | 4·8 (3·9 to 6·0) | −82·4% (−85·4 to −78·7) | −85·0% (−87·5 to −81·9) | −78·4% (−80·4 to −75·8) | −75·4% (−77·0 to −73·7) | |
| Oceania | 783 (599 to 1000) | 9·3 (7·4 to 11·5) | 693 (497 to 937) | 4·4 (3·3 to 5·7) | 5530 (4580 to 6530) | 74·5 (64·7 to 84·9) | 6690 (5650 to 7860) | 46·0 (39·6 to 52·8) | −11·5% (−38·6 to 28·1) | −52·7% (−65·5 to −34·4) | 21·1% (14·0 to 30·2) | −38·2% (−41·3 to −34·5) | |
| Southeast Asia | 37 400 (30 300 to 46 800) | 6·9 (5·7 to 8·4) | 10 700 (9320 to 12 400) | 1·8 (1·6 to 2·1) | 213 000 (169 000 to 266 000) | 38·1 (30·9 to 47·3) | 120 000 (98 900 to 144 000) | 20·1 (16·6 to 24·4) | −71·3% (−77·6 to −63·2) | −73·1% (−78·8 to −66·2) | −43·7% (−47·9 to −38·0) | −47·2% (−49·8 to −43·8) | |
| Sub-Saharan Africa | 174 000 (143 000 to 208 000) | 29·3 (25·4 to 33·8) | 144 000 (117 000 to 176 000) | 14·3 (12·2 to 16·7) | 1 110 000 (920 000 to 1 350 000) | 167·3 (143·4 to 194·1) | 1 200 000 (998 000 to 1 450 000) | 96·3 (82·6 to 111·7) | −17·0% (−32·2 to 3·7) | −51·3% (−58·6 to −42·0) | 7·8% (4·8 to 11·2) | −42·4% (−43·4 to −41·5) | |
| Central sub-Saharan Africa | 14 500 (11 400 to 18 300) | 19·6 (15·9 to 23·7) | 9990 (7720 to 12 900) | 8·9 (6·8 to 11·2) | 107 000 (88 200 to 128 000) | 135·3 (116·9 to 155·9) | 128 000 (108 000 to 153 000) | 87·2 (75·6 to 99·6) | −31·1% (−49·4 to −10·9) | −54·6% (−65·4 to −42·7) | 19·8% (11·8 to 29·0) | −35·5% (−38·6 to −32·0) | |
| Eastern sub- Saharan Africa | 69 000 (57 800 to 81 900) | 32·7 (28·1 to 37·4) | 42 400 (35 800 to 50 700) | 13·2 (11·5 to 15·1) | 429 000 (354 000 to 519 000) | 171·7 (146·6 to 198·2) | 436 000 (364 000 to 525 000) | 97·3 (83·4 to 112·3) | −38·5% (−50·1 to −24·2) | −59·5% (−65·1 to −52·5) | 1·8% (−3·0 to 6·8) | −43·4% (−45·0 to −41·7) | |
| Southern sub- Saharan Africa | 4070 (3500 to 4610) | 8·0 (7·0 to 8·9) | 4130 (3520 to 4770) | 6·1 (5·3 to 6·9) | 33 200 (27 700 to 39 600) | 59·6 (51·0 to 69·0) | 34 000 (29 000 to 39 500) | 45·8 (39·3 to 52·6) | 1·4% (−15·9 to 23·0) | −24·0% (−35·8 to −10·7) | 2·5% (−3·1 to 9·2) | −23·2% (−25·6 to −20·5) | |
| Western sub- Saharan Africa | 86 200 (69 300 to 107 000) | 34·7 (29·1 to 41·2) | 87 600 (68 300 to 110 000) | 18·4 (15·0 to 22·1) | 544 000 (447 000 to 665 000) | 198·8 (170·6 to 230·9) | 602 000 (494 000 to 737 000) | 105·8 (90·1 to 124·1) | 1·6% (−19·7 to 31·2) | −47·0% (−56·2 to −35·3) | 10·6% (8·1 to 13·2) | −46·8% (−47·6 to −45·8) | |
Data in parentheses are 95% uncertainty intervals. Count data are presented to three significant figures and rates are presented to one decimal place. SDI=Socio-demographic Index. GBD=Global Burden of Diseases, Injuries, and Risk Factors Study.