Table 2.
Under-5 meningitis incidence and mortality rates and counts in 1990 and 2019, and percentage change in deaths, cases, and incidence and mortality rates between 1990 and 2019, by SDI quintile, globally, and for seven GBD super-regions and 21 GBD regions
|
Mortality |
Incidence |
Percentage change (1990–2019) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1990 counts | Mortality rate (per 100 000), 1990 | 2019 counts | Mortality rate (per 100 000), 2019 | 1990 counts | Incidence rate (per 100 000), 1990 | 2019 counts | Incidence rate (per 100 000), 2019 | Mortality | Mortality rate | Incidence | Incidence rate | ||
| Global | 284 000 (237 000 to 339 000) | 45·0 (37·4 to 53·6) | 112 000 (87 400 to 145 000) | 16·9 (13·2 to 21·9) | 1 970 000 (1 460 000 to 2 650 000) | 312·0 (231·6 to 418·6) | 1 280 000 (947 000 to 1 710 000) | 192·4 (142·8 to 258·6) | −60·5% (−69·2 to −49·8) | −62·3% (−70·6 to −52·1) | −35·3% (−36·5 to −34·0) | −38·3% (−39·5 to −37·0) | |
| Low SDI | 118 000 (94 200 to 146 000) | 122·3 (97·5 to 151·4) | 77 600 (59 100 to 102 000) | 45·4 (34·6 to 59·8) | 719 000 (549 000 to 938 000) | 744·8 (568·8 to 971·2) | 684 000 (517 000 to 904 000) | 400·2 (302·8 to 529·4) | −34·3% (−49·2 to −14·0) | −62·9% (−71·3 to −51·4) | −4·9% (−7·6 to −2·1) | −46·3% (−47·8 to −44·7) | |
| Low-middle SDI | 93 100 (76 600 to 114 000) | 55·3 (45·6 to 67·8) | 24 400 (19 000 to 31 500) | 14·1 (11·0 to 18·3) | 639 000 (473 000 to 854 000) | 380·0 (281·0 to 507·6) | 348 000 (254 000 to 466 000) | 202·0 (147·2 to 270·2) | −73·8% (−80·3 to −65·0) | −74·4% (−80·7 to −65·9) | −45·6% (−47·4 to −43·6) | −46·8% (−48·6 to −44·9) | |
| Middle SDI | 55 600 (47 000 to 65 500) | 27·1 (22·9 to 32·0) | 8320 (6680 to 10 400) | 4·5 (3·6 to 5·6) | 420 000 (301 000 to 572 000) | 205·0 (147·0 to 279·4) | 175 000 (125 000 to 243 000) | 95·0 (68·1 to 132·2) | −85·0% (−88·4 to −80·9) | −83·4% (−87·1 to −78·8) | −58·3% (−59·7 to −56·6) | −53·7% (−55·2 to −51·7) | |
| High-middle SDI | 15 400 (13 400 to 17 800) | 14·7 (12·8 to 17·0) | 1560 (1310 to 1860) | 1·9 (1·6 to 2·2) | 147 000 (107 000 to 202 000) | 140·4 (102·2 to 192·9) | 49 900 (35 100 to 70 900) | 60·4 (42·5 to 85·8) | −89·9% (−92·1 to −87·2) | −87·2% (−90·0 to −83·8) | −66·0% (−67·8 to −63·9) | −57·0% (−59·3 to −54·4) | |
| High SDI | 1710 (1610 to 1840) | 3·0 (2·8 to 3·2) | 296 (256 to 334) | 0·6 (0·5 to 0·6) | 45 900 (32 100 to 65 800) | 79·7 (55·6 to 114·1) | 18 000 (12 300 to 26 100) | 34·4 (23·5 to 49·9) | −82·7% (−85·2 to −80·5) | −81·0% (−83·7 to −78·5) | −60·7% (−62·2 to −59·5) | −56·8% (−58·5 to −55·4) | |
| Central Europe, eastern Europe, and central Asia | 4180 (3880 to 4520) | 11·7 (10·9 to 12·7) | 450 (368 to 565) | 1·6 (1·3 to 2·0) | 55 800 (42 300 to 75 600) | 156·7 (118·6 to 212·2) | 21 200 (15 100 to 30 200) | 77·1 (54·8 to 109·5) | −89·2% (−91·4 to −86·2) | −86·0% (−88·8 to −82·1) | −62·0% (−65·0 to −58·4) | −50·8% (−54·8 to −46·2) | |
| Central Asia | 1900 (1680 to 2130) | 20·0 (17·7 to 22·5) | 186 (142 to 269) | 1·9 (1·5 to 2·8) | 20 200 (15 800 to 26 200) | 213·2 (166·7 to 276·3) | 10 100 (7290 to 14 100) | 105·6 (76·1 to 147·5) | −90·2% (−92·7 to −85·0) | −90·3% (−92·8 to −85·2) | −50·0% (−55·6 to −42·7) | −50·5% (−56·1 to −43·3) | |
| Central Europe | 801 (737 to 882) | 9·0 (8·3 to 9·9) | 42 (32 to 52) | 0·7 (0·6 to 0·9) | 8680 (6440 to 11 800) | 97·2 (72·1 to 132·5) | 2530 (1780 to 3660) | 44·8 (31·4 to 64·8) | −94·8% (−96·1 to −93·3) | −91·8% (−93·9 to −89·4) | −70·8% (−73·2 to −67·6) | −53·8% (−57·6 to −48·8) | |
| Eastern Europe | 1480 (1370 to 1620) | 8·6 (8·0 to 9·4) | 223 (183 to 267) | 1·8 (1·5 to 2·2) | 26 900 (19 600 to 37 300) | 156·4 (113·6 to 216·6) | 8600 (5920 to 12 500) | 69·7 (48·0 to 101·2) | −84·9% (−88·1 to −81·8) | −78·9% (−83·4 to −74·6) | −68·1% (−70·4 to −65·4) | −55·4% (−58·7 to −51·6) | |
| High income | 2230 (2110 to 2390) | 3·6 (3·4 to 3·9) | 380 (327 to 435) | 0·7 (0·6 to 0·8) | 51 600 (36 600 to 73 000) | 84·0 (59·6 to 118·9) | 19 000 (13 100 to 27 100) | 33·4 (23·0 to 47·7) | −83·0% (−85·6 to −80·5) | −81·7% (−84·4 to −79·0) | −63·2% (−64·7 to −61·9) | −60·3% (−61·9 to −58·9) | |
| Australasia | 51 (44 to 58) | 3·3 (2·9 to 3·8) | 12 (9 to 15) | 0·7 (0·5 to 0·8) | 1640 (1180 to 2250) | 106·2 (76·4 to 146·0) | 1040 (706 to 1530) | 57·1 (38·8 to 84·0) | −76·6% (−82·6 to −69·8) | −80·2% (−85·2 to −74·3) | −36·5% (−44·6 to −28·2) | −46·2% (−53·0 to −39·1) | |
| High-income Asia Pacific | 228 (195 to 265) | 2·2 (1·9 to 2·6) | 17 (14 to 19) | 0·2 (0·2 to 0·3) | 10 600 (7160 to 15 700) | 103·2 (69·8 to 153·0) | 3320 (2230 to 4820) | 45·5 (30·6 to 66·1) | −92·7% (−94·0 to −91·0) | −89·7% (−91·6 to −87·4) | −68·6% (−70·5 to −66·7) | −55·9% (−58·5 to −53·2) | |
| High-income North America | 587 (539 to 662) | 2·7 (2·5 to 3·1) | 137 (122 to 152) | 0·7 (0·6 to 0·7) | 9940 (6380 to 15 300) | 46·2 (29·7 to 71·3) | 2200 (1490 to 3200) | 10·5 (7·1 to 15·2) | −76·7% (−80·0 to −73·3) | −76·1% (−79·5 to −72·6) | −77·9% (−79·5 to −75·4) | −77·3% (−79·0 to −74·8) | |
| Southern Latin America | 552 (499 to 608) | 10·7 (9·7 to 11·8) | 81 (60 to 105) | 1·7 (1·2 to 2·2) | 5620 (4360 to 7460) | 108·9 (84·5 to 144·5) | 2180 (1550 to 3100) | 44·8 (32·0 to 63·8) | −85·3% (−89·4 to −80·3) | −84·4% (−88·8 to −79·1) | −61·3% (−66·0 to −56·2) | −58·8% (−63·9 to −53·4) | |
| Western Europe | 817 (760 to 894) | 3·6 (3·3 to 3·9) | 134 (111 to 157) | 0·6 (0·5 to 0·7) | 23 800 (17 200 to 33 000) | 103·7 (74·8 to 143·7) | 10 300 (7150 to 14 800) | 46·7 (32·5 to 67·1) | −83·6% (−86·9 to −80·7) | −82·9% (−86·3 to −79·8) | −56·9% (−59·3 to −54·7) | −55·0% (−57·6 to −52·7) | |
| Latin America and Caribbean | 12 400 (11 200 to 14 000) | 24·8 (22·4 to 28·0) | 2040 (1520 to 2630) | 4·2 (3·2 to 5·5) | 71 600 (54 000 to 95 400) | 143·2 (107·9 to 190·6) | 25 000 (18 000 to 35 100) | 52·1 (37·4 to 73·1) | −83·6% (−88·2 to −78·2) | −82·9% (−87·7 to −77·3) | −65·0% (−67·3 to −61·9) | −63·6% (−66·0 to −60·3) | |
| Andean Latin America | 868 (715 to 1050) | 15·9 (13·1 to 19·3) | 112 (80 to 161) | 1·8 (1·3 to 2·5) | 4500 (3480 to 5790) | 82·5 (63·9 to 106·3) | 2120 (1540 to 2900) | 33·5 (24·4 to 45·8) | −87·1% (−91·1 to −80·7) | −88·9% (−92·4 to −83·4) | −52·9% (−57·7 to −47·2) | −59·5% (−63·6 to −54·6) | |
| Caribbean | 2600 (2080 to 3190) | 62·9 (50·2 to 77·0) | 947 (633 to 1350) | 24·0 (16·0 to 34·2) | 8470 (6590 to 10 800) | 204·7 (159·2 to 260·3) | 5070 (3750 to 6730) | 128·4 (95·0 to 170·3) | −63·6% (−77·2 to −44·2) | −61·9% (−76·1 to −41·5) | −40·1% (−44·9 to −35·4) | −37·3% (−42·2 to −32·3) | |
| Central Latin America | 2970 (2670 to 3300) | 13·0 (11·7 to 14·4) | 365 (261 to 490) | 1·7 (1·2 to 2·3) | 21 400 (15 900 to 28 700) | 93·5 (69·5 to 125·4) | 6930 (4870 to 9940) | 32·0 (22·5 to 45·9) | −87·7% (−91·5 to −83·1) | −87·0% (−91·1 to −82·2) | −67·6% (−70·2 to −64·1) | −65·8% (−68·5 to −62·1) | |
| Tropical Latin America | 5980 (5130 to 7090) | 34·1 (29·2 to 40·4) | 613 (472 to 767) | 3·8 (2·9 to 4·8) | 37 300 (27 500 to 50 200) | 212·4 (156·9 to 285·9) | 10 900 (7730 to 15 900) | 67·7 (47·9 to 98·5) | −89·7% (−92·5 to −86·4) | −88·8% (−91·8 to −85·2) | −70·7% (−73·5 to −67·4) | −68·1% (−71·1 to −64·5) | |
| North Africa and Middle East | 12 500 (9850 to 16 400) | 23·5 (18·5 to 30·7) | 2310 (1740 to 3100) | 3·9 (2·9 to 5·2) | 84 700 (63 700 to 112 000) | 158·8 (119·4 to 210·1) | 48 800 (35 500 to 67 700) | 81·7 (59·4 to 113·4) | −81·5% (−87·0 to −74·1) | −83·5% (−88·4 to −76·9) | −42·4% (−46·7 to −37·5) | −48·5% (−52·4 to −44·2) | |
| South Asia | 77 100 (62 300 to 93 300) | 47·6 (38·5 to 57·7) | 21 400 (16 200 to 28 200) | 13·0 (9·9 to 17·1) | 659 000 (479 000 to 893 000) | 407·1 (296·0 to 551·8) | 338 000 (245 000 to 461 000) | 205·7 (148·8 to 280·3) | −72·3% (−80·3 to −62·2) | −72·7% (−80·6 to −62·9) | −48·7% (−51·0 to −46·5) | −49·5% (−51·7 to −47·4) | |
| Southeast Asia, east Asia, and Oceania | 54 100 (44 300 to 66 300) | 30·0 (24·6 to 36·8) | 6500 (5300 to 7950) | 4·6 (3·8 to 5·7) | 277 000 (194 000 to 385 000) | 153·4 (107·6 to 213·8) | 80 600 (57 400 to 110 000) | 57·4 (40·9 to 78·6) | −88·0% (−90·8 to −84·6) | −84·6% (−88·2 to −80·3) | −70·9% (−71·9 to −69·6) | −62·6% (−63·9 to −60·9) | |
| East Asia | 25 700 (21 300 to 30 300) | 21·4 (17·7 to 25·3) | 1510 (1210 to 1840) | 1·8 (1·4 to 2·2) | 131 000 (88 100 to 191 000) | 109·1 (73·6 to 159·1) | 21 200 (14 500 to 30 300) | 25·2 (17·2 to 36·1) | −94·1% (−95·6 to −92·2) | −91·7% (−93·7 to −88·9) | −83·8% (−84·9 to −82·6) | −76·9% (−78·4 to −75·2) | |
| Oceania | 579 (413 to 785) | 58·9 (42·0 to 79·9) | 469 (305 to 687) | 25·3 (16·5 to 37·1) | 3270 (2480 to 4220) | 333·0 (252·2 to 428·9) | 3780 (2920 to 4840) | 204·2 (157·6 to 261·6) | −18·9% (−49·7 to 32·1) | −56·9% (−73·3 to −29·8) | 15·4% (6·1 to 28·4) | −38·7% (−43·6 to −31·8) | |
| Southeast Asia | 27 900 (20 900 to 37 200) | 46·8 (35·2 to 62·6) | 4520 (3510 to 5800) | 8·3 (6·4 to 10·6) | 143 000 (104 000 to 193 000) | 239·6 (175·2 to 324·9) | 55 600 (40 200 to 75 600) | 102·1 (73·8 to 138·7) | −83·8% (−88·5 to −77·4) | −82·3% (−87·4 to −75·3) | −61·0% (−62·8 to −58·9) | −57·4% (−59·4 to −55·1) | |
| Sub-Saharan Africa | 122 000 (95 800 to 155 000) | 135·7 (106·9 to 172·5) | 79 200 (59 200 to 104 000) | 47·8 (35·8 to 63·0) | 773 000 (591 000 to 1 010 000) | 862·9 (659·9 to 1126·3) | 743 000 (561 000 to 982 000) | 448·3 (338·6 to 592·9) | −34·9% (−49·7 to −13·1) | −64·8% (−72·8 to −53·0) | −4·0% (−6·8 to −0·9) | −48·0% (−49·6 to −46·4) | |
| Central sub-Saharan Africa | 10 100 (7230 to 13 700) | 93·5 (67·3 to 127·6) | 3400 (2240 to 5270) | 16·4 (10·8 to 25·5) | 74 100 (56 500 to 94 300) | 689·4 (525·4 to 876·8) | 70 500 (53 700 to 93 600) | 340·6 (259·4 to 452·4) | −66·2% (−77·2 to −50·1) | −82·5% (−88·2 to −74·1) | −4·9% (−12·6 to 4·3) | −50·6% (−54·6 to −45·8) | |
| Eastern sub-Saharan Africa | 45 100 (35 600 to 56 200) | 125·2 (98·9 to 156·1) | 17 100 (12 700 to 23 000) | 26·7 (19·8 to 35·9) | 288 000 (217 000 to 378 000) | 798·9 (603·6 to 1049·1) | 245 000 (184 000 to 327 000) | 382·0 (287·5 to 509·2) | −62·0% (−71·5 to −48·9) | −78·6% (−84·0 to −71·3) | −14·8% (−18·7 to −10·4) | −52·2% (−54·3 to −49·7) | |
| Southern sub- Saharan Africa | 1810 (1370 to 2270) | 25·3 (19·1 to 31·7) | 784 (571 to 1070) | 9·7 (7·1 to 13·3) | 15 900 (11 800 to 21 200) | 222·0 (164·7 to 295·5) | 11 300 (8330 to 15 200) | 139·5 (102·9 to 187·2) | −56·7% (−69·8 to −36·1) | −61·6% (−73·2 to −43·4) | −29·1% (−32·5 to −25·2) | −37·2% (−40·2 to −33·7) | |
| Western sub- Saharan Africa | 64 600 (50 000 to 84 600) | 181·2 (140·3 to 237·2) | 57 800 (42 700 to 76 000) | 79·5 (58·8 to 104·4) | 396 000 (304 000 to 517 000) | 1108·7 (853·4 to 1449·5) | 416 000 (314 000 to 546 000) | 571·7 (431·4 to 751·1) | −10·5% (−32·0 to 21·3) | −56·1% (−66·7 to −40·5) | 5·1% (2·4 to 8·0) | −48·4% (−49·8 to −47·0) | |
Data in parentheses are 95% uncertainty intervals. Count data are presented to three significant figures and rates are presented to one decimal place. SDI=Socio-demographic Index. GBD=Global Burden of Diseases, Injuries, and Risk Factors Study.