Table 3.
Neonatal meningitis incidence and mortality rates and counts in 1990 and 2019, and percentage change in deaths, cases, and incidence and mortality rates between 1990 and 2019, by SDI quintile, globally, and for seven GBD super-regions and 21 GBD regions
|
Mortality |
Incidence |
Percentage change (1990–2019) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1990 counts | Mortality rate (per 100 000), 1990 | 2019 counts | Mortality rate (per 100 000), 2019 | 1990 counts | Incidence rate (per 100 000), 1990 | 2019 counts | Incidence rate (per 100 000), 2019 | Mortality | Mortality rate | Incidence | Incidence rate | ||
| Global | 30 600 (26 600 to 36 200) | 296·7 (257·2 to 350·9) | 14 000 (11 200 to 18 200) | 137·2 (109·5 to 177·8) | 134 000 (96 300 to 182 000) | 1301·2 (932·4 to 1767·2) | 87 300 (62 300 to 121 000) | 854·8 (609·2 to 1183·3) | −54·2% (−63·1 to −42·4) | −53·8% (−62·8 to −41·8) | −35·0% (−36·5 to −33·4) | −34·3% (−35·8 to −32·7) | |
| Low SDI | 13 700 (11 700 to 16 600) | 778·1 (661·5 to 942·2) | 9330 (7290 to 12 200) | 329·3 (257·2 to 429·4) | 57 800 (42 400 to 77 200) | 3278·8 (2403·4 to 4381·1) | 52 800 (38 200 to 72 100) | 1863·6 (1346·4 to 2545·6) | −31·9% (−46·5 to −13·3) | −57·7% (−66·8 to −46·1) | −8·6% (−12·0 to −5·3) | −43·2% (−45·3 to −41·1) | |
| Low-middle SDI | 9700 (7920 to 11 800) | 342·3 (279·4 to 416·7) | 3270 (2510 to 4330) | 122·3 (94·0 to 161·8) | 40 200 (28 600 to 55 100) | 1419·6 (1007·7 to 1944·6) | 22 000 (15 400 to 30 700) | 822·4 (574·3 to 1149·1) | −66·3% (−75·2 to −53·3) | −64·3% (−73·7 to −50·5) | −45·3% (−47·1 to −43·3) | −42·1% (−44·0 to −39·9) | |
| Middle SDI | 5510 (4700 to 6680) | 169·3 (144·5 to 205·4) | 1170 (930 to 1470) | 43·0 (34·2 to 54·2) | 26 000 (18 000 to 36 100) | 798·3 (553·2 to 1110·4) | 9550 (6530 to 13 700) | 351·6 (240·3 to 502·6) | −78·8% (−83·6 to −72·7) | −74·6% (−80·3 to −67·3) | −63·2% (−64·6 to −62·0) | −56·0% (−57·6 to −54·5) | |
| High-middle SDI | 1470 (1320 to 1690) | 93·9 (83·9 to 107·4) | 184 (152 to 225) | 15·4 (12·7 to 18·8) | 8150 (5730 to 11 500) | 519·1 (364·9 to 730·6) | 2240 (1540 to 3240) | 186·7 (128·2 to 270·5) | −87·5% (−90·1 to −84·3) | −83·6% (−87·1 to −79·5) | −72·5% (−74·0 to −71·1) | −64·0% (−66·0 to −62·2) | |
| High SDI | 210 (193 to 229) | 23·4 (21·4 to 25·5) | 48 (41 to 56) | 6·1 (5·2 to 7·1) | 2130 (1530 to 2990) | 236·8 (170·4 to 332·4) | 690 (487 to 1000) | 87·7 (61·8 to 127·1) | −77·3% (−80·9 to −73·2) | −74·0% (−78·2 to −69·4) | −67·6% (−69·2 to −66·0) | −63·0% (−64·9 to −61·2) | |
| Central Europe, eastern Europe, and Central Asia | 653 (606 to 719) | 131·2 (121·8 to 144·5) | 66 (53 to 83) | 16·6 (13·4 to 20·8) | 3150 (2360 to 4200) | 633·8 (474·2 to 843·4) | 826 (595 to 1170) | 208·0 (149·7 to 293·6) | −89·9% (−92·0 to −87·3) | −87·4% (−90·0 to −84·1) | −73·8% (−76·0 to −71·6) | −67·2% (−70·0 to −64·4) | |
| Central Asia | 274 (244 to 309) | 185·4 (165·3 to 209·2) | 34 (26 to 48) | 24·0 (18·1 to 33·2) | 1400 (1100 to 1740) | 948·8 (742·4 to 1182·4) | 438 (326 to 598) | 305·9 (227·7 to 417·6) | −87·4% (−90·7 to −82·1) | −87·0% (−90·4 to −81·6) | −68·7% (−72·6 to −64·0) | −67·8% (−71·8 to −62·9) | |
| Central Europe | 110 (99 to 127) | 86·7 (77·5 to 99·5) | 8 (6 to 11) | 10·2 (7·8 to 13·0) | 469 (355 to 613) | 368·1 (279·0 to 481·9) | 92 (68 to 130) | 112·9 (83·0 to 158·3) | −92·4% (−94·3 to −90·1) | −88·2% (−91·1 to −84·6) | −80·3% (−81·8 to −78·5) | −69·3% (−71·7 to −66·6) | |
| Eastern Europe | 269 (243 to 312) | 120·7 (108·9 to 140·2) | 23 (19 to 28) | 13·4 (10·8 to 16·4) | 1280 (887 to 1820) | 576·8 (398·6 to 819·2) | 295 (201 to 435) | 171·7 (116·7 to 252·9) | −91·4% (−93·7 to −89·3) | −88·9% (−91·8 to −86·2) | −77·0% (−78·8 to −75·6) | −70·2% (−72·5 to −68·4) | |
| High income | 275 (256 to 298) | 28·8 (26·8 to 31·2) | 58 (49 to 68) | 6·8 (5·7 to 8·0) | 2510 (1850 to 3450) | 262·7 (193·5 to 360·8) | 748 (537 to 1070) | 87·4 (62·8 to 124·7) | −78·8% (−82·3 to −74·8) | −76·3% (−80·3 to −71·8) | −70·2% (−71·7 to −68·9) | −66·7% (−68·4 to −65·2) | |
| Australasia | 8 (6 to 9) | 32·1 (26·7 to 38·2) | 2 (2 to 3) | 8·5 (6·5 to 11·0) | 74 (52 to 102) | 306·8 (217·7 to 423·4) | 35 (25 to 50) | 126·2 (89·8 to 178·8) | −69·2% (−77·9 to −57·9) | −73·5% (−81·0 to −63·8) | −52·2% (−59·2 to −45·8) | −58·9% (−64·9 to −53·3) | |
| High-income Asia Pacific | 39 (33 to 46) | 25·8 (21·9 to 30·4) | 3 (2 to 3) | 2·6 (2·1 to 3·0) | 401 (282 to 580) | 267·3 (188·4 to 386·6) | 88 (58 to 132) | 83·3 (55·6 to 125·5) | −93·0% (−94·6 to −91·2) | −90·0% (−92·3 to −87·5) | −78·1% (−80·4 to −75·7) | −68·8% (−72·0 to −65·3) | |
| High-income North America | 59 (51 to 69) | 16·9 (14·6 to 19·9) | 21 (19 to 24) | 6·6 (5·9 to 7·5) | 431 (275 to 651) | 123·6 (78·9 to 186·8) | 111 (72 to 159) | 34·6 (22·6 to 49·6) | −64·0% (−70·2 to −56·5) | −60·7% (−67·5 to −52·6) | −74·3% (−76·2 to −71·5) | −72·0% (−74·1 to −68·9) | |
| Southern Latin America | 71 (62 to 80) | 89·0 (78·8 to 100·8) | 9 (6 to 13) | 12·5 (8·8 to 17·1) | 391 (313 to 489) | 493·2 (394·6 to 616·3) | 101 (76 to 137) | 137·6 (103·6 to 186·0) | −87·0% (−91·0 to −81·8) | −86·0% (−90·3 to −80·4) | −74·1% (−77·4 to −70·1) | −72·1% (−75·6 to −67·8) | |
| Western Europe | 100 (90 to 111) | 28·2 (25·6 to 31·4) | 23 (18 to 28) | 7·0 (5·6 to 8·5) | 1210 (898 to 1670) | 343·2 (254·1 to 471·7) | 413 (300 to 587) | 125·6 (91·2 to 178·6) | −77·0% (−82·0 to −71·3) | −75·3% (−80·6 to −69·1) | −66·0% (−68·3 to −63·7) | −63·4% (−66·0 to −61·0) | |
| Latin America and Caribbean | 1280 (1120 to 1490) | 160·0 (139·4 to 185·6) | 304 (207 to 419) | 41·1 (28·0 to 56·6) | 4830 (3550 to 6440) | 601·9 (442·4 to 802·6) | 1350 (970 to 1840) | 182·7 (131·2 to 248·6) | −76·3% (−84·3 to −65·4) | −74·3% (−82·9 to −62·4) | −72·0% (−73·6 to −70·6) | −69·7% (−71·4 to −68·1) | |
| Andean Latin America | 105 (83 to 137) | 115·7 (91·7 to 150·4) | 18 (13 to 27) | 18·6 (12·8 to 26·7) | 391 (296 to 505) | 430·7 (325·4 to 556·1) | 139 (103 to 184) | 139·8 (103·9 to 185·0) | −82·4% (−88·7 to −73·9) | −83·9% (−89·7 to −76·2) | −64·4% (−68·0 to −60·7) | −67·5% (−70·8 to −64·2) | |
| Caribbean | 440 (313 to 603) | 644·4 (459·0 to 883·3) | 209 (127 to 318) | 339·8 (206·2 to 515·9) | 760 (576 to 978) | 1113·3 (843·2 to 1431·9) | 418 (302 to 552) | 678·0 (490·2 to 896·2) | −52·4% (−73·0 to −19·1) | −47·3% (−70·1 to −10·3) | −45·1% (−49·9 to −38·9) | −39·1% (−44·5 to −32·3) | |
| Central Latin America | 384 (335 to 438) | 102·6 (89·6 to 116·9) | 52 (37 to 71) | 15·6 (11·2 to 21·2) | 1610 (1220 to 2090) | 429·0 (325·0 to 557·7) | 365 (272 to 489) | 109·4 (81·5 to 146·5) | −86·4% (−90·6 to −81·3) | −84·8% (−89·4 to −79·1) | −77·2% (−78·6 to −75·4) | −74·5% (−76·0 to −72·5) | |
| Tropical Latin America | 355 (305 to 416) | 131·9 (113·4 to 154·5) | 24 (19 to 30) | 9·8 (7·6 to 12·4) | 2070 (1420 to 2920) | 770·4 (525·7 to 1083·0) | 429 (288 to 633) | 175·5 (117·6 to 259·0) | −93·3% (−95·0 to −91·3) | −92·6% (−94·5 to −90·4) | −79·3% (−81·5 to −77·9) | −77·2% (−79·6 to −75·7) | |
| North Africa and Middle East | 1850 (1450 to 2390) | 209·9 (164·9 to 271·3) | 389 (276 to 541) | 42·3 (30·0 to 58·8) | 6320 (4560 to 8450) | 718·6 (517·7 to 960·7) | 2820 (2020 to 3960) | 306·9 (219·6 to 430·6) | −79·0% (−85·9 to −68·4) | −79·9% (−86·5 to −69·7) | −55·3% (−58·9 to −51·7) | −57·3% (−60·7 to −53·8) | |
| South Asia | 7820 (6420 to 9470) | 292·4 (240·1 to 353·7) | 3120 (2320 to 4230) | 123·6 (92·1 to 167·8) | 35 800 (24 900 to 50 300) | 1339·3 (929·6 to 1879·0) | 18 500 (12 500 to 26 400) | 733·7 (497·6 to 1046·4) | −60·2% (−72·5 to −43·7) | −57·7% (−70·8 to −40·2) | −48·4% (−50·6 to −46·2) | −45·2% (−47·5 to −42·8) | |
| Southeast Asia, east Asia, and Oceania | 4160 (3290 to 5450) | 145·2 (114·6 to 190·3) | 627 (489 to 805) | 30·8 (24·0 to 39·5) | 16 900 (11 500 to 23 700) | 589·9 (401·5 to 826·0) | 4500 (3090 to 6300) | 221·3 (151·7 to 309·6) | −84·9% (−89·1 to −79·3) | −78·8% (−84·7 to −70·9) | −73·4% (−74·4 to −72·1) | −62·5% (−64·0 to −60·7) | |
| East Asia | 1400 (1150 to 1660) | 73·5 (60·7 to 87·3) | 128 (100 to 157) | 10·9 (8·5 to 13·3) | 6830 (4360 to 9950) | 359·2 (229·5 to 523·7) | 1000 (650 to 1450) | 84·9 (55·3 to 122·8) | −90·8% (−93·2 to −88·1) | −85·2% (−89·1 to −80·8) | −85·4% (−86·2 to −84·5) | −76·4% (−77·8 to −75·0) | |
| Oceania | 46 (30 to 68) | 274·6 (181·5 to 408·8) | 46 (26 to 72) | 149·6 (83·0 to 233·0) | 249 (183 to 329) | 1488·1 (1092·8 to 1962·6) | 285 (204 to 387) | 916·6 (657·5 to 1247·7) | 0·9% (−46·5 to 78·6) | −45·5% (−71·1 to −3·6) | 14·1% (0·7 to 29·5) | −38·4% (−45·7 to −30·1) | |
| Southeast Asia | 2720 (2000 to 3920) | 286·3 (210·9 to 412·7) | 453 (339 to 615) | 54·7 (41·0 to 74·3) | 9830 (6950 to 13 300) | 1035·9 (732·0 to 1398·0) | 3220 (2240 to 4470) | 389·1 (270·2 to 540·3) | −83·3% (−88·7 to −75·1) | −80·9% (−87·1 to −71·4) | −67·3% (−68·8 to −65·6) | −62·4% (−64·2 to −60·5) | |
| Sub-Saharan Africa | 14 600 (12 200 to 18 400) | 885·7 (738·5 to 1115·3) | 9460 (7220 to 12 500) | 344·0 (262·6 to 456·3) | 64 800 (47 500 to 86 700) | 3933·5 (2881·7 to 5263·3) | 58 600 (42 500 to 80 100) | 2130·9 (1546·7 to 2914·2) | −35·1% (−49·2 to −16·7) | −61·2% (−69·6 to −50·1) | −9·5% (−12·6 to −6·1) | −45·8% (−47·7 to −43·7) | |
| Central sub- Saharan Africa | 1540 (1040 to 2220) | 769·5 (523·4 to 1111·4) | 750 (484 to 1200) | 223·8 (144·5 to 359·0) | 6620 (4810 to 8760) | 3317·3 (2410·4 to 4389·0) | 5560 (4060 to 7590) | 1660·4 (1210·6 to 2265·6) | −51·1% (−70·1 to −17·4) | −70·9% (−82·2 to −50·8) | −15·9% (−25·6 to −7·0) | −49·9% (−55·7 to −44·7) | |
| Eastern sub- Saharan Africa | 5990 (4930 to 7500) | 900·9 (740·9 to 1127·4) | 3000 (2230 to 4040) | 282·6 (210·7 to 381·3) | 24 300 (17 800 to 32 400) | 3650·9 (2674·3 to 4876·7) | 19 300 (13 900 to 26 900) | 1819·8 (1309·6 to 2538·8) | −49·9% (−62·5 to −34·1) | −68·6% (−76·5 to −58·7) | −20·5% (−24·6 to −15·5) | −50·2% (−52·8 to −47·0) | |
| Southern sub- Saharan Africa | 195 (155 to 242) | 168·1 (134·2 to 209·1) | 110 (79 to 157) | 87·8 (63·0 to 125·0) | 1060 (758 to 1450) | 912·5 (654·7 to 1255·2) | 729 (516 to 1020) | 581·1 (411·3 to 814·2) | −43·4% (−60·9 to −14·7) | −47·7% (−63·9 to −21·3) | −31·0% (−35·4 to −26·7) | −36·3% (−40·3 to −32·4) | |
| Western sub- Saharan Africa | 6870 (5600 to 8910) | 1030·2 (840·1 to 1336·3) | 5600 (4270 to 7490) | 455·9 (347·7 to 609·3) | 32 800 (24 200 to 43 700) | 4924·8 (3634·3 to 6563·5) | 33 000 (24 100 to 44 500) | 2686·1 (1959·9 to 3622·4) | −18·4% (−37·6 to 7·3) | −55·7% (−66·2 to −41·8) | 0·5% (−2·9 to 3·7) | −45·5% (−47·3 to −43·7) | |
Data in parentheses are 95% uncertainty intervals. Count data are presented to three significant figures and rates are presented to one decimal place. Neonates are defined as those aged 0–27 days. SDI=Socio-demographic Index. GBD=Global Burden of Diseases, Injuries, and Risk Factors Study.