Table 8.

Safety—by lesion based on RTOG criteria

Characteristic	Grade	Description	(n = 1196)a
Highest RTOG toxicity grade	1	Follicular, faint, or dull erythema; epilation; dry desquamation; decreased sweating	843/1196 (70.5%)
	2	Tender or bright erythema, patchy moist desquamation; moderate edema	292/1196 (24.4%)
	3	Confluent, moist desquamation other than skin folds; pitting edema	50/1196 (4.2%)
	4	Ulceration, hemorrhage, necrosis	11/1196 (0.9%)

RTOG radiation treatment oncology group

^a703 lesions missing RTOG grading