Table 2.
The expression levels of GABA-related genes in each group
| WT mice | 3xTg mice | p | |
| Gabra1 expression in 12-week-old | 1.00±0.07 | 0.99±0.06 | 0.87 |
| Gabra1 expression in 36-week-old | 1.11±0.06 | 1.05±0.06 | 0.11 |
| Gabra1 expression in 52-week-old | 0.87±0.08 | 0.84±0.02 | 0.31 |
| Gabrr2 expression in 12-week-old | 1.00±0.25 | 0.95±0.25 | 0.73 |
| Gabrr2 expression in 36-week-old | 1.69±0.49 | 1.13±0.17 | 0.02 |
| Gabrr2 expression in 52-week-old | 1.27±0.50 | 1.44±0.45 | 0.53 |
| Gabrg3 expression in 12-week-old | 1.00±0.08 | 0.88±0.09 | 0.02 |
| Gabrg3 expression in 36-week-old | 1.12±0.14 | 0.92±0.09 | 0.005 |
| Gabrg3 expression in 52-week-old | 0.78±0.10 | 0.70±0.05 | 0.08 |
| Gabrr1 expression in 12-week-old | 1.00±0.04 | 0.95±0.04 | 0.12 |
| Gabrr1 expression in 36-week-old | 0.99±0.04 | 0.97±0.03 | 0.09 |
| Gabrr1 expression in 52-week-old | 1.03±0.17 | 0.89±0.04 | 0.001 |
Values are means±standard deviation. The expression levels of GABA-related genes in each group are shown divided by the average expression level in WT mice at 12-week-old. WT, wild-type; 3xTg, 3xTg-AD model.