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. 2023 Jun 27;94(1):1–17. doi: 10.3233/JAD-220460

Table 2.

Xanthophylls in AD and HE donor brains and healthy elderly brains

Disease Status ZEA LUT ANLUT XMiAD α-CRYPT β-CRYPT TOT. XAN
AD
  Grey 4.2±0.5 7.3±1.0 2.9±0.4 26.9±3.9 3.7±0.5 18.1±3.1 65.0±7.7
  White 2.4±0.4 3.5±0.6 2.6±0.4 20.4±3.2 3.5±0.5 12.7±1.5 46.7±5.5
  G versus W p= 0.009 0.0006 ns ns ns ns ns
  AD versus HE p= 0.002 0.04 0.05 0.006 ns ns ns
HE
  Grey 8.0±1.6 10.0±1.7 4.0±0.6 7.0±2.4 3.8±0.6 16.0±2.2 52.8±6.6
  White 4.8±1.7 5.7±1.9 4.0±1.2 15.5±6.4 4.5±1.4 15.4±4.8 54.2±17.3

Xanthophyll concentrations (Mean +SE in pmol/gram) in grey and white matter of donor HE and AD brains. p-values result from ANOVA with Bonferroni-Dunn posthoc tests. ZEA, zeaxanthin; LUT, lutein; ANLUT, anhydrolutein; XMiAD, xanthophyll metabolite increased in AD; α-CRYPT, alpha-Cryptoxanthin; β-CRYPT, β-cryptoxanthin; TOT. XAN, total xanthophylls.