Table 2.
Disease Status | ZEA | LUT | ANLUT | XMiAD | α-CRYPT | β-CRYPT | TOT. XAN |
AD | |||||||
Grey | 4.2±0.5 | 7.3±1.0 | 2.9±0.4 | 26.9±3.9 | 3.7±0.5 | 18.1±3.1 | 65.0±7.7 |
White | 2.4±0.4 | 3.5±0.6 | 2.6±0.4 | 20.4±3.2 | 3.5±0.5 | 12.7±1.5 | 46.7±5.5 |
G versus W p= | 0.009 | 0.0006 | ns | ns | ns | ns | ns |
AD versus HE p= | 0.002 | 0.04 | 0.05 | 0.006 | ns | ns | ns |
HE | |||||||
Grey | 8.0±1.6 | 10.0±1.7 | 4.0±0.6 | 7.0±2.4 | 3.8±0.6 | 16.0±2.2 | 52.8±6.6 |
White | 4.8±1.7 | 5.7±1.9 | 4.0±1.2 | 15.5±6.4 | 4.5±1.4 | 15.4±4.8 | 54.2±17.3 |
Xanthophyll concentrations (Mean +SE in pmol/gram) in grey and white matter of donor HE and AD brains. p-values result from ANOVA with Bonferroni-Dunn posthoc tests. ZEA, zeaxanthin; LUT, lutein; ANLUT, anhydrolutein; XMiAD, xanthophyll metabolite increased in AD; α-CRYPT, alpha-Cryptoxanthin; β-CRYPT, β-cryptoxanthin; TOT. XAN, total xanthophylls.