Table 1. Incidence of Diagnosed Vitiligo Overall and by Sex, Age, and Race and Ethnicity From 2015 to 2019.
| Group | Vitiligo cases, No. | Patients, No. | Follow-up time, PY | Crude incidence rate, per 100 000 PY (95% CI) | Standardized incidence rate, per 100 000 PY (95% CI)a | Standardized incidence rate ratio, (95% CI)a |
|---|---|---|---|---|---|---|
| Overall | 1605 | 2 980 778 | 7 081 566 | 22.7 (21.6-23.8) | 22.6 (21.5-23.8) | NA |
| Sex | ||||||
| Female | 905 | 1 697 610 | 4 093 581 | 22.1 (20.7-23.6) | 21.9 (20.5-23.4) | 0.94 (0.85-1.03) |
| Male | 700 | 1 283 168 | 2 987 985 | 23.4 (21.7-25.2) | 23.4 (21.7-25.3) | 1 [Reference] |
| Age group, y | ||||||
| 0-17 (Pediatric) | 293 | 626 539 | 1 408 038 | 20.8 (18.5-23.3) | 20.8 (18.5-23.4) | 0.89 (0.79-1.01) |
| 0-9 | 162 | 373 329 | 808 543 | 20.0 (17.1-23.4) | 20.2 (17.2-23.5) | NA |
| 10-17 | 131 | 253 210 | 599 496 | 21.9 (18.3-25.9) | 21.9 (18.3-26.0) | NA |
| ≥18 (Adult) | 1312 | 2 354 239 | 5 673 527 | 23.1 (21.9-24.4) | 23.3 (22.1-24.6) | 1 [Reference] |
| 18-29 | 167 | 403 457 | 884 482 | 18.9 (16.1-22.0) | 19.3 (16.4-22.6) | NA |
| 30-39 | 195 | 352 656 | 812 244 | 24.0 (50.8-27.6) | 24.8 (20.8-27.6) | NA |
| 40-49 | 218 | 358 629 | 872 007 | 25.0 (21.8-28.5) | 24.7 (21.4-28.2) | NA |
| 50-59 | 272 | 432 337 | 1 090 563 | 24.9 (22.1-28.1) | 24.9 (22.0-28.1) | NA |
| 60-69 | 256 | 398 390 | 1 023 230 | 25.0 (22.0-28.3) | 25.3 (22.2-28.6) | NA |
| ≥70 | 204 | 408 770 | 991 001 | 20.6 (17.9-23.6) | 20.9 (18.1-24.0) | NA |
| Race and ethnicityb | ||||||
| Asian American | 33 | 36 886 | 77 686 | 42.5 (29.2-59.7) | 41.2 (28.2-58.2) | 2.20 (1.89-2.57) |
| Black | 252 | 333 794 | 851 482 | 30.0 (26.1-33.5) | 29.6 (26.0-33.6) | 1.58 (1.48-1.69) |
| Hispanic/Latino | 34 | 40 086 | 92 491 | 36.8 (25.5-51.4) | 37.3 (25.7-52.4) | 2.00 (1.71-2.32) |
| White | 916 | 2 002 447 | 4 827 627 | 19.0 (17.8-20.2) | 18.7 (17.5-20.0) | 1 [Reference] |
| Other or multiracialc | 126 | 177 964 | 405 268 | 31.1 (25.9-37.0) | 31.1 (25.9-37.1) | 1.66 (1.53-1.81) |
Abbreviations: NA, not applicable; PY, person-years.
a
Overall incidence was standardized by age and sex using the direct method and population estimates from the 2019 US Community Survey.14 Sex-specific and race-specific incidences were standardized by age. Age-specific incidences were standardized by sex.
b
Data were missing for 389 601 patients. Missing data were included in the estimates of vitiligo incidence for the overall group and sex and age subgroups.
c
Other included Asian/Pacific Islander, Native American or Alaska Native, Native Hawaiian, or other (not specified).